Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 11 of 11 for “"hippocampal plasticity"”.
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Stress and Hippocampal Plasticity
… alterations are reversible, suggesting that the hippocampal system experiences a certain degree of plasticity in response to stress. This dissertation examines the effects of chronic restraint stress on several parameters of hippocampal plasticity, including dentate gyrus neurogenesis, polysialic …
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Aerobic Exercise and Hippocampal Plasticity in Young Adults with Depression
… promise in reducing symptoms and promoting brain plasticity in MDD. A relationship between symptom severity, hippocampus volume and N-acetyl-aspartate (NAA) concentration, a marker of neuron density/viability, has been shown. The relationship of these variables to fitness (as assessed by volume of …
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The effects of parental experience on cognition, anxiety-like behaviour, and hippocampal plasticity in a biparental species.
… spatial cognition, anxiety-like behaviour, and hippocampal neuroplasticity-related measures (microglia and perineuronal net expression) in both sexes of the same species, the degu. Degus are biparental rodents allowing us to examine maternal and paternal experiences in addition to maternal …
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Changes in Hippocampal Plasticity and HPA Axis Function Following Postnatal Exposure to Di(2-Ethylhexyl) Phthalate in Rats
… aimed to determine whether phthalates affect hippocampal development, and whether there is an associated activation of HPA axis. DEHP was injected in juvenile rats daily from PND 16 – PND 22. Brain tissue samples were analyzed by immunohistochemistry to quantify developing neurons. The Golgi – …
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Interactions of Thyroid Hormones and Nerve Growth Factor in Normal Development of the Rat Hippocampus and Basal Forebrain and in Recovery From Early Hypothyroid Retardation
… found that hypothyroidism results in decreased hippocampal NGF levels, while up-regulating its receptors: the p75 neurotrophin and p140 trk A receptor. We propose that declining levels hippocampal NGF results in decreased trophic support for basal forebrain cholinergic neurons, leading to a …
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Photobiomodulation of hippocampal neurogenesis for inducing resilience against Alzheimer’s disease
Adult hippocampal neurogenesis (AHN) is the process by which neural stem cells in the hippocampal dentate gyrus proliferate and differentiate to form new granule neurons that integrate into hippocampal circuitry, facilitating hippocampal plasticity throughout life. AHN is severely diminished in …
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Cardiorespiratory fitness as a modulator of hippocampal subfield structure and function in cognitive aging
… paradigms in humans. Age-related impairment in hippocampally-dependent cognition emphasizes the importance of identifying modulators of hippocampal plasticity. Critically, studies in older adults have demonstrated that greater cardiorespiratory fitness (CRF) is associated with greater volume of …
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Genetic and behavioral discrimination of dopamine 1 and 5 receptors in hippocampal dependent memory consolidation
… very little is known how dopamine functions in hippocampal dependent learning. It was only until recently that dopamine-containing neurons were found to project to the hippocampus. Even less understood are the expression patterns of DA receptors within the hippocampus and this is underlined by …
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Low-Frequency-Induced Synaptic Potentiation: a Paradigm Shift in the Field of Memory-Related Plasticity Mechanisms?
It is assumed that plasticity involving up-and down regulation of synaptic strength (i.e., long-term potentiation, LTP; long-term depression, LTD) mediates learning and memory processes. Typically, high-frequency stimulation (HFS) of afferent fibers results in LTP, while low-frequency stimulation …
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Investigations on the role of the gut microbiota in hippocampal neuroplasticity and behaviour throughout the lifespan
… shown to harness the ability to influence neuroplasticity within the hippocampus of the brain, as well as hippocampus-dependent behavioural processes. The hippocampus is one of the few brain regions in which new neurons are born throughout life, an ability that is critical for specific cognitive …
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The Manipulation Of Apical Dendritic Plasticity And The Consequences For The Effects of Chronic Stress
… is a cell adhesion molecule present during plasticity in development and also following chronic stress in the hippocampus. PSA-NCAM removal did not cause cell death on its own or following chronic stress by multiple measures. Phosphorylated-Tau is present in the hippocampus of severely …