Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 3 of 3 for “"hippocampal culture"”.
-
Mechanisms of plasticity at the axon initial segment
… perturbation in input. Here, I use a dissociated hippocampal culture model to investigate plasticity at the AIS in more depth. In order to reduce the variability brought about by cell-subtype heterogeneity, I focussed on a single excitatory subtype, the dentate granule cell (DGC), which I show …
-
Targeting Ion Channels to Distal Dendrites
… distal localization and its importance in hippocampal function. Using dissociated and organotypic hippocampal culture systems, we show that HCN1 surface expression is activity dependent. However, the axons that innervate the distal compartment are not required for HCN1 localization. Our …
-
Heterogenous Change in Neuronal Bursts Following Recovery from Activity Silencing
Silencing of activity in hippocampal neuronal cultures was used to study how dynamic neuronal activity achieves a state of homeostasis, using calcium imaging to detect neuronal firing patterns. Recovering cultures were found to display abnormal activity patterns after 48hrs of exposure to …