Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"hippocampal CA1 neurons"”.
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The hippocampal "Event Code" : implications from Descartes to Gridworld
… lap events. Using this maze, we reported hippocampal CA1 neurons whose activity was modulated not only by spatial location, but also lap number. These "event-specific rate remapping" (ESR) cells remain lap-specific even when the maze length was unpredictably altered within trials, …
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Ampa Receptor Dysregulation And Therapeutic Interventions In A Mouse Model Of Cdkl5 Deficiency Disorder
… of R59X mice, suggesting an increase in hippocampal GluA2-lacking AMPARs, which are calcium permeable and have significant roles in regulating neuronal plasticity and excitability. Indeed, decreased hippocampal GluA2 was accompanied by inward rectification of AMPAR currents in whole-cell …
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The role of redox oscillation in circadian physiology of the suprachiasmatic nucleus and hippocampus
… appears to modulate membrane excitability in hippocampal CA1 neurons. Our results demonstrate that 1) the SCN redox oscillation is a modulator of circadian physiology at the level of phase-shifting response to light, 2) the circadian redox oscillation shows interdependency with the molecular …
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Neural Computation Through Synaptic Dynamics in Serotonergic Networks
… from being passive connections between spiking neurons, synapses display striking short-term dynamics, undergo long-term changes in strength, and sculpt network-level processes in a complex manner. These synaptic dynamics, both in time and across space, may be a fundamental determinant of …
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Computational techniques to interpret the neural code underlying complex cognitive processes
… prefrontal cortex at the level of individual neurons. To start, the thesis begins by investigating memory and social cognition in the context of healthy and diseased states that use non-invasive methods (i.e. fMRI and animal behavioural studies). The main body of the thesis then shifts to …