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Showing 1 to 20 of 81 for “"hindlimb"”.
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Effect of induced hindlimb length difference on bodymounted inertial sensor measures of hindlimb lameness in horses
This study has investigated the effect of induced hindlimb length difference on differences in minimum and maximum pelvic heights in horses trotting in a straight line and lungeing on both hard and soft surfaces. The horses were trotted in a straight line and lunged in both directions on both hard …
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The effects of testosterone propionate on hindlimb immobilized rats
… The rats in group II were castrated and their hindlimbs were immobilized using a plaster cast. The animals in this group also received daily injections of sesame oil. The group III rats were also castrated and casted, but they received a daily injection of 5 mg testosterone propionate. The …
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Sex Differences in Collateral Remodeling Following Hindlimb Arterial Occlusion
<p>Clinical evidence indicates a higher incidence of peripheral arterial occlusive disease and associated likelihood of critical limb ischemia in women, as well as worse prognosis and decreased survival post myocardial infarction. Therefore, understanding the possible differences in underlying …
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Modeling Gait Muscle-Reflexes Through Hindlimb Characterization in Rodents
The complexity of gait modeling ranges from simple models that represent the leg as two linear springs to more complex ones that comprise muscle-tendons and spinal muscle-reflexes. However, the more complex models fail to have a strong empirical basis for muscle-reflex definition and function. To …
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Optimization of a pericyte therapy to improve muscle recovery following hindlimb immobilization
… divided into four groups (n=6/group). Mice hindlimbs were immobilized in full dorsiflexion via a surgical staple inserted through the center of the foot and body of the gastrocnemius for 2 weeks. At 2 weeks post immobilization, staples were removed and either pericytes (NG2+CD45-CD31-[Lin-], …
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Endothelial Cell-Specific Knockout of Meis1 Protects Ischemic Hindlimb Through Vascular Remodeling
… of arteriogenesis and angiogenesis using hindlimb ischemia model of transgenic neonatal mice. The long-term goal is to develop a new treatment for patients with PAD. Three separate but related studies were planned to complete the proposed research aims. To better understand the role of …
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Comparative Plasma Proteomics in Muscle Atrophy Induced by Cancer Cachexia and Hindlimb Unloading
… Methods: 35 male C57BL/6J mice were assigned to hindlimb unloading (HU), Lewis Lung Carcinoma (LLC), or control groups. HU animals were hindlimb-unloaded for 1 week to induce disuse atrophy. LLC cells were injected into the right hind-flank to induce cancer cachexia. Tumors developed for …
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Molecular imaging of spatio-temporal distribution of angiogenesis in hindlimb ischemia model and diabetic milieu
… for the evaluation of angiogenesis in the rabbit hindlimb ischemia model. Furthermore, diabetes mellitus (DM) was induced, to study the effects of this pathology on the spatio-temporal distribution of angiogenesis. In order to evaluate the whole spectrum of endogenous process of collateralization …
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Forelimb and hindlimb adjustments to treadmill speed during quadrupedal locomotion after a lateral spinal hemisection in adult cats.
… in forelimb cycle duration and increase in hindlimb cycle duration. The dissociation of fore-hindlimb rhythms lead to the appearance of 2-1 coordination which was not influenced by stepping speed. Step and stride length modulation was maintained after SCI, however, as speeds increased, …
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Transport and exchange of amino acids from plasma, erythrocytes, peptides and serum proteins across the hindlimb of calves fed soy or urea purified diets
… and arteriovenous (A/V) differences across the hindlimbs were determined on growing Holstein steer calves (130 kg) fed purified diets containing scy protein or urea as the sole source of dietary nitrogen. Animals were fed at hourly intervals in a constantly lighted environment in order to …
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Control of mechanically stable movement by spinalized frogs
… of trajectories produced by spinalized frogs. Hindlimb movements in frogs were measured and phasic force perturbations were applied by a Phantom robot (Sensable Tech., Inc) attached at the ankle. EMGs were recorded from 12 hindlimb muscles and used to trigger the perturbations in both …
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Age related changes and tissue distribution of parvalbumin in both normal and dystrophic 129 ReJ mice.
In murine muscular dystrophy (strain 129 ReJ), hindlimb muscle contains a functionally defective thiol protease inhibitor (TPI) which has been implicated in the onset and progression of the disease in this strain of mice. More recently, and through the work of several researchers, this protease …
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Limbs gone batty : the role of the anterior-posterior patterning signal, Sonic Hedgehog, in the development of the unique bat limb
… skeletal structure of the bat forelimb and hindlimb provides a new and exciting model for the field of evolutionary developmental biology, which seeks to reveal the molecular mechanisms behind vertebrate limb diversity. The digits of the bat forelimb, excluding the thumb, are considerably …
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Frog Spinal Motoneurons: Their Supraspinal Synaptic Input and Anatomical Localization
… flexor and extensor motoneurons innervating the hindlimb. These EPSPs appeared to be generated monosynaptically on the somas and proximal dendrites of the motoneurons. Chromatolysis was used to map the location of motoneurons innervating hindlimb muscles in the bullfrog, Rana catesbiana. These …
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Effects of pentoxifylline on exercising skeletal muscle vascular control in rats with chronic heart failure
… to CHF (p<0.05 for both). At rest, total hindlimb skeletal muscle BF and VC were not different between groups (p>0.05). However, during exercise PTX increased total hindlimb BF (CHF: 83±9, CHF+PTX: 114±8 ml·min[superscript]-[superscript]1·100g[superscript]-[superscript]1, p<0.05) and VC …
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Remote, non-invasive ischaemic preconditioning of skeletal muscle flaps against ischaemic necrosis : efficacy and mechanism
… cycles of ischaemia and reperfusion, using a hindlimb tourniquet.
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Investigation into the use of an epidural morphine sulfate and detomidine hydrochloride combination in horses: Part 1: efficacy in alleviation of hindlimb pain, Part 2: long-term systemic and local effects
… of the left tarsocrural joint was used to create hindlimb lameness in 11 horses. Caudal epidural catheters were placed and advanced to the lumbosacral region. Baseline heart and respiratory rates were recorded and horses were videotaped at a walk and trot. Treated horses received 0.2 mg/kg …
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Studies in Amphibian Limb Development and Regeneration
… most abrupt losses in the ability to regenerate hindlimbs after amputation. We have dealt successfully with the issue of variability in regeneration data by eliminating developmentally abnormal tadpoles from experimental pools and ensuring that sample sizes were large for statistically assessing …
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