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Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.

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Showing 1 to 20 of 129 for “"high-density lipoprotein"”.

  1. The regulation of blood coagulation by high-density lipoprotein particles

    Oslakovic, CeciliaDepartment of Laboratory Medicine, Lund University2010

    High-density lipoprotein (HDL) has anti-atherogenic properties and the plasma level of HDL cholesterol correlates inversely with the risk of coronary artery disease. The atheroprotective functions of HDL can be explained by its function in the reverse cholesterol transport. Blood coagulation is …

    lund Repository record

  2. Roles of human plasma phospholipid transfer protein in high-density lipoprotein metabolism

    Tu, An-YueUniversity of Illinois at Urbana-Champaign2011

    … than apo-A-I. However, the apoproteins added to lipoproteins did not yield significant effects. The PL transfer activity of PLTP was considerably higher than that of LTP, especially when synthetic lipid particles rather than natural lipoproteins were used as donor particles. Plasma PLTP and LTP …

    uiuc Repository record

  3. The Effects of Cholesteryl Ester Transfer Protein Inhibition on High Density Lipoprotein Function

    Shrestha, SudichhyaUNSW, Sydney2018

    … a positive correlation between elevated plasma high density lipoprotein cholesterol (HDL-C) levels and a reduced risk of major cardiovascular events. HDLs have several potential cardioprotective functions, the most extensively studied of which is their ability to remove excess cholesterol from …

    unsw Repository record

  4. The role of high density lipoprotein compositional and functional heterogeneity in metabolic disease

    Gordon, Scott M.University of Cincinnati2012

    High density lipoproteins (HDL) are complexes of phospholipid, cholesterol and protein that circulate in the blood. Epidemiological studies have demonstrated a strong inverse correlation between plasma levels of HDL associated cholesterol (HDL-C) and the incidence of cardiovascular disease (CVD). …

    ohiolink Repository record

  5. Investigating high-density lipoprotein (HDL) subfractions, composition and functionality in people living with HIV

    Hudson, PeterDepartment of Medicine2022

    … distribution, composition, and functionality of high-density lipoprotein (HDL) subfractions are altered in the presence of cardiovascular risk factors. We aimed to explore whether HIV and/or ART modulate HDL subfractions and functionality in a population of people living with HIV (PLWH). Methods: …

    cape-town Repository record

  6. Comparison of total and high-density lipoprotein cholesterol in male recreational swimmers and sedentary controls

    Battle, Robert A.Virginia Polytechnic Institute and State University1985

    Total and high-density lipoprotein cholesterol (TC and HDL-C) and TC/HDL-C ratio were compared in 30 adult male recreational swimmers and 21 sedentary controls. Percentage of body fat, number of cigarettes smoked daily, and daily alcohol consumption were assessed for both groups. Maximum workout …

    vt Repository record

  7. Isolation and Lipid Binding Properties of the Low Molecular Weight Protein Components of Bovine High Density Lipoprotein

    Patterson, Bruce WayneUniversity of Illinois at Urbana-Champaign2014

    … comparable to intact bovine HDL. Isopycnic density gradient ultracentrifugational isolations of complexes demonstrated that DMPC/bovine ApoC recombinants routinely banded within the density range of intact bovine HDL, 1.063 - 1.125 g/ml.

    uiuc Repository record

  8. The effect of an endurance and weight training program on plasma total cholesterol and high-density lipoprotein-cholesterol

    Webb, Kelsie R.Virginia Polytechnic Institute and State University1987

    … training program on plasma total cholesterol, high-density lipoproteins, body composition. Experimental subjects were randomly assigned to the treatment conditions. The subjects trained three days a week for nine weeks. The R group ran for 30 minutes a session at 75% predicted maximum HR. The W …

    vt Repository record

  9. Understanding the relationship between high-density lipoprotein (HDL) subclass distribution and functionality in patients at risk of cardiovascular disease

    Woudberg, NicholasDepartment of Medicine2017

    … include obesity, ethnicity and hypertension. High-density lipoprotein (HDL) has traditionally served as a marker for CVD risk. Latest studies, however, propose that the composition and subclass distribution and the anti-atherogenic function of HDL are more accurate predictors of CVD risk. We …

    cape-town Repository record

  10. THE ROLE OF HEPATOCYTE ATP-BINDING CASSETTE TRANSPORTER A1 (ABCA1) AND APOLIPOPROTEIN M (APOM) IN HIGH DENSITY LIPOPROTEIN (HDL) METABOLISM

    Bashore, Alexander CusaWake Forest University2018

    … binding cassette transporter A1 (ABCA1) and apolipoprotein M (apoM) both have been shown to influence high density lipoprotein (HDL) metabolism. Hepatic ABCA1, a plasma membrane protein, functions to transport free cholesterol (FC) and phospholipids across the plasma membrane to apolipoproteins, …

    wfu Repository record

  11. Exploring the relationship between shifts in high-density lipoprotein (HDL) particle subclass distribution/functionality and cardiac function in doxorubicin (DOX)-induced cardiotoxicity

    Abrahams, Carmelita BiancaDepartment of Medicine2024

    … with dyslipidaemia, however changes in high-density lipoprotein (HDL) particle subclass distribution, composition and functionality are unknown. We therefore aimed to investigate whether changes in HDL particle subclass distribution, composition and functionality in breast cancer …

    cape-town Repository record

  12. Tissue specific regulation of the high density lipoprotein (HDL) receptor, scavenger receptor Class B, Type I (SR-BI) by the scaffold protein PDZK1

    Fenske, Sara AnneMassachusetts Institute of Technology2008

    … adaptor protein that binds the Cterminus of the high-density lipoprotein (HDL) receptor SR-BI. Abolishing PDZK1 expression in PDZK1 knockout (KO) mice leads to a post-transcriptional, tissue-specific decrease in SR-BI protein level and an increase in total plasma cholesterol carried in …

    mit Repository record

  13. Investigating the Role of Standing Blood Pressure Measurement and the Association Between High-Density Lipoprotein and Skeletal Muscle Mitochondrial Function in Pre-Hypertensive Humans

    Giacona, John Michael2026

    … and 2) characterize the associations between high-density lipoprotein (HDL) and skeletal muscle mitochondrial function. Herein, we are the first to observe that standing BP measurements are highly accurate in detecting HTN when compared to seated BP. These findings demonstrate standing BP as a …

    utswmed Repository record

  14. Analysis of Genetic Factors Affecting High Density Lipoprotein Levels and ApoAll Levels in C57 B1/6J and FVB/N Wildtype Mice Using a QTL Mapping Approach

    Barrios, Judith2014

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    shu-thes Repository record

  15. Role of the SAFE pathway and the mitochondria in HDL cholesterol (and its constituent sphingosine-1-phosphate) induced cardioprotection

    Hacking, DamianDivision of Cardiology2011

    High density lipoprotein cholesterol (HDL) and its component sphingosine-1-phosphate (S1P) protect against myocardial infarction. Recently, the SAFE (survivor activating factor enhancement) pathway, involving tumour necrosis factor (TNF) and the transcription factor signal transducer and activator …

    cape-town Repository record

  16. Spontaneous lipid transfers between low density lipoproteins and reconstituted high density lipoproteins

    Bottum, Kathleen MaryUniversity of Illinois at Urbana-Champaign2011

    … important components in the metabolism of low density lipoprotein (LDL) and high density lipoprotein (HDL). Cholesterol spontaneously transfers from LDL to HDL; phospholipid transfer proceeds in the reverse direction. Reconstituted HDL (rHDL) particles were employed in this study. Cholesterol …

    uiuc Repository record

  17. Association of dietary and phosphatidylcholine supplement intake with cardio-metabolic biomarkers among normo- and hyperlipidaemic individuals

    Jan, Majd MohammedYounisOxford Brookes University2019

    … of cellular membranes and plays a vital role in lipoprotein metabolism. Many studies have investigated the effects of phosphatidylcholine on lipid profiles; however, results have been inconsistent, therefore the precise effects of dietary phosphatidylcholine remain unclear. This project aimed to: …

    oxford-brookes Repository record

  18. Structural and functional studies of the C-terminal domain of human apolipoprotein A-I: Limited proteolysis and deletion mutagenesis

    Ji, YongUniversity of Illinois at Urbana-Champaign2011

    … produce a large N-terminal fragment of human apolipoprotein A-I (apoA-I). Digestion of reconstituted high density lipoprotein (rHDL) prepared with apoA-I and dipalmitoyl phosphatidylcholine (DPPC) or palmitoyloleoyl PC (POPC) by chymotrypsin, trypsin, elastase, or subtilisin generated a major …

    uiuc Repository record

  19. Cardioprotective role of signal transducer activator of transcription 3 (STAT-3) against ischaemai reperfusion injuries

    King, Jonathan ChanDivision of Cardiology2011

    … 1 phosphate (S1P) is a major constituent of high density lipoprotein (HDL) cholesterol. Both S1P preconditioning and ischaemic postconditioning reduce myocardial damage following an ischaemia-reperfusion insult but the mechanisms involved remain unclear. Janus kinase/Signal transducer and …

    cape-town Repository record

  20. Anabolic-androgenic steroids : a series of meta-analyses

    Spence, John Cochrane1997

    … effects were observed for lean body mass, thigh circumference, bench press, and squat; while moderate negative effects were found for Apo-AI, high-density lipoprotein, sex hormone binding-globulin, and albumin. Small positive treatment effects were observed for hemoglobin, hematocrit, body …

    concordia Repository record

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