Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"high dose methotrexate"”.
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Aspects on optimisation of High Dose Methotrexate treatment in children with Acute Lymphoblastic Leukaemia
… in other malignancies have been developed. Methotrexate is a major component of most contemporary childhood ALL treatment protocols. The main objectives of this thesis were to investigate how methotrexate concentration time data from high dose methotrexate intravenous infusions relate to …
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Burkitt and Burkitt-like lymphoma/leukaemia at Groote Schuur Hospital from 2005 to 2014: a retrospective review
Introduction: South Africa has the highest global burden of human immunodeficiency virus (HIV). The HIV seropositive population is at increased risk of developing non-Hodgkin lymphoma, particularly high grade aggressive subtypes such as Burkitt- and Burkittlike lymphoma (also known as B-cell …
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Langfristige Entwicklung Zytostatika-induzierter Nierenfunktionsstörungen bei pädiatrisch-onkologischen Patienten
… cisplatin, carboplatin, etoposide, and methotrexate are investigated.Altogether, 55.7% of the patients show a normal renal function. Slight damages seem to improve rather than serious damages that show a tendency to persistence. In the group of the children treated for leukemia …
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Establishment and characterisation of chemoresistant osteosarcoma cell lines by single and multi-agent induced strategies
… The combination of cisplatin, doxorubicin and high-dose methotrexate is the standard treatment for most patients. Surgery combined with chemotherapy has improved the survival rate for osteosarcoma patients to 60% - 70%. However, most of the patients with metastatic or recurrent osteosarcoma …