Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 62 for “"heterogeneous population"”.
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Measuring Single Cell Responses to Lapatinib In A Heterogeneous Population
… mechanisms can lead to adaptive resistance cell populations based on single cell dynamics. Models to predict the internal environment of the cell by the phenotype and vice versa will be a very novel approach to understand the adaptive resistance mechanism and to overcome it. Here, I propose to …
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Normalization Among Heterogeneous Population Confers Stimulus Discriminability on the Macaque Face Patch Neurons
… a high-dimensional space spanned by the neural population. We showed that this was because neuronal population was quite heterogeneous, yet changing response systematically as stimulus parameter changed. Few neurons showed MAX-like behavior. These findings were explained by divisive …
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Modeling reduction of pandemic influenza using pharmaceutical and non pharmaceutical interventions in a heterogeneous population
… analysis of influenza modeling in a heterogeneous population. The majority of existing epidemiological literature models influenza spread in a statistically homogeneous population, but the model-based inclusion of heterogeneity by contact rate, susceptibility, and infectivity …
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Topics in Heterogeneous Group Testing
… methods of classification and estimation in a heterogeneous population. The goal of classification is to identify all positives among those individuals screened using initial group testing results and the subsequent process of decoding of positive pools. Many decoding algorithms have been …
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Detection and characterization of rat hepatic stellate cells in a 3-dimensional, perfused, liver bioreactor
… zonation, and liver cell types comprise a heterogeneous population from the portal triad where the blood flows into the sinusoids to the central vein area where the blood flows out of the sinusoids. Liver cell types are dynamic responders to environmental cues from soluble factors to …
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Statistical algorithms for Cluster Weighted Models
… the joint probability of data coming from a heterogeneous population. In this thesis first we investigate statistical properties of CWM from both theoretical and numerical point of view for both Gaussian and Student-t CWM. Then we introduce a novel family of twelve mixture models, all nested …
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Households and Neighborhoods Among Free People of Color in New Orleans: A View from the Census, 1850-1860
… structures, and occupations that reveal a heterogeneous population that eludes simple definitions. In particular this study focuses on mixed-race households to shed light on this segment of the free colored population that is mostly unstudied and generally misrepresented. This study also …
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Modelling pandemic influenza progression using Spatiotemporal Epidemiological Modeller (STEM)
… of a Poisson disease model of a homogenous population, which is built as an extension of the implemented SI disease model in the STEM. Next, it proposes an algorithm to port a Poisson disease model of a heterogeneous population into the STEM. The development of the two new diseases plugins …
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CHARACTERIZATION OF CD4+ T CELL-INDUCING EPITOPES OF ISLETSPECIFIC GLUCOSE-6-PHOSPHATASE CATALYTIC SUBUNIT-RELATED PROTEIN (IGRP) THAT PREVENT AUTOIMMUNITY
… peptide-primed CD4+ T cells is indicative of a heterogeneous population of regulatory cells which protect against T1D development via IL-10 and TGF-B production. The ability to induce regulatory T cells makes IGRP peptides P3 and P7 attractive targets for diabetes therapy and prevention.
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Observations in Lipid Membrane Systems
… and further observations were made. We found a heterogeneous population with respect to the behavior of the vesicles. We categorized these observations with respect to the appearance of the lipid membrane to characterize the phenomenon.
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The determinants of successful partnerships : a case study of the GrandFamilies community, Boston MA
… needed when trying to serve this relatively new population. There are three components to this analysis; (1) a description of the target population;(2) a summation of the initial survey that was used to develop the GrandFamilies concept;(3) and a the follow-up survey, which was used to explore …
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Reflections on the Development of Children of Alcoholics
… how COAs are studied, they are found to be a heterogeneous population. Specifically, this study's results points out that they are indeed heterogeneous, yet similar in that all participants in this study, it could be argued, exhibit some vulnerability in regard to parental alcoholism.
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ADDUCINS AFFECT CORTICAL NEUROGENESIS BY REGULATING PROGENITORS¿ MORPHOLOGY AND FATE
… and to cortical folding. BPs are a highly heterogeneous population: they can be classified in basal intermediate progenitors (bIPs) and basal radial glia (bRG) based on morphology and proliferative capability. It was observed that a higher number of cell processes positively correlates with …
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The Function of Phosphatidylinositol 4-Kinase III-Beta in Trypanosoma Brucei
… analysis reveals internal accumulation of a heterogeneous population of vesicles, abnormal positioning of organelles and a loss of cell polarity. Scanning EM reveals a twisted morphology most likely due to an alteration in the microtubule cytoskeleton. Dividing TbPI4KIII-ß RNAi trypanosomes …
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The role of microvesicles in EMT and tumour microenvironment
Microvesicles are heterogeneous population of micro-particles released constitutively and upon induction from healthy and unhealthy cells. The role of cancer cell derived-MV in intercellular communication gains an intensive aria of research. The influence of leukaemia cell derived-MVs in this study …
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Cell Migration and Morphogenesis during Formation and Repair of Zebrafish Skeletal Muscle
… led to the hypothesis that abc's could be a heterogeneous population of cells which segregate into different behaviour groups, depending on their later fate. Furthermore, slow muscle fibres were observed in vivo to migrate collectively as a chain of slow muscle cells that reaches from somite …
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Heterogeneity in the Pitx2ON Population in the Mouse Superior Colliculus
… integration. Pitx2ON neurons, a glutamatergic population in the intermediate SC, are known to drive spatially oriented head movements. These neurons project to various regions, including tecto-spinal systems that govern head and eye movements and the mesocorticolimbic system, hinting at roles …
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Adipose-Derived Adult Stem Cells as Trophic Mediators of Tendon Regeneration
… new therapy for equine flexor tendonitis. This heterogeneous population of cells may improve tendon healing via the production of growth and chemotactic factors capable of recruiting endogenous stem cells and increasing extracellular matrix production by tendon fibroblasts (TFBL). The purpose of …
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Essays on the economics of income taxation
… optimal taxation and can be easily extended to a heterogeneous population of taxpayers. A simple formula for optimal marginal rates for high income earners is derived as a function of the two elasticities of earnings and the thickness of the income distribution. Optimal income tax simulations are …
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Bad Apples, Bad Barrels, and the Structure of Marketing Channel Relationships: Analyses of the Propensity for Opportunism and Opportunistic Behaviors
… analysis treats marketing channel managers as a heterogeneous population and investigates the impact of individual traits on their behaviors in business relationships. At the dyadic level, I modify standard microeconomics models to incorporate norms of fairness. Finally, the extra-dyadic level of …
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