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Showing 1 to 20 of 115 for “"herpesvirus"”.
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HERPESVIRUS ATELES: ISOLATION AND CHARACTERIZATION OF A HERPESVIRUS OF SPIDER MONKEYS.
HERPESVIRUS ATELES: ISOLATION AND CHARACTERIZATION OF A HERPESVIRUS OF SPIDER MONKEYS.
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Effects of Marek's Disease Herpesvirus and Turkey Herpesvirus Upon Immunity to Eimeria Acervulina in Young Chickens
… investigators for years. Infection with MD herpesvirus has been shown to inhibit immunity of chicks to three species of Eimeria. Herpesvirus from turkeys (HVT) is used commercially as a vaccine against MD. This investigation studied the response to primary and secondary exposures to E. …
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Multi-modal imaging of herpesvirus infection
Herpes simplex virus (HSV)-1 is a large, enveloped DNA virus that undergoes a complex assembly pathway in the cell. Capsids assemble in the nucleus, cross the nuclear envelope into the cytoplasm by budding and fusion through the nuclear membranes, and acquire a proteinaceous ‘tegument’ layer in the …
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Intrinsic Control Strategies for Herpesvirus-based Vaccine Vectors
Herpesvirus-based vectors have been used in vaccine strategies to target zoonotic diseases such as Ebola and human monkeypox, through eliciting a highly immunogenic response. We are investigating strategies to attenuate the virus and control its ability to replicate and persist, while maintaining …
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Impaired Control of Chronic Herpesvirus Infection in Tissue Resident Macrophages During Coinfection with Intestinal Parasite and Other Cell-intrinsic Herpesvirus Interactions
Gammaherpesviruses are chronic pathogens that infect lymphocytes, such as B cells, dendritic cells, and macrophages. Reactivation of gammaherpesviruses is thought to induce lymphomas and can be caused by a variety of signals, such as HDAC inhibitors. While some of these signals are known, it is …
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Characterization of the Surface Proteins of the Anatid herpesvirus
A plaque purified isolate, Anatid herpesvirus (AHV-ppc3) of the Holland strain of AHV (American Type Culture Collection No. VR684) was propagated in chicken embryo fibroblasts and purified by differential and buoyant density sedimentation through thtough sucrose gradients. A total of 17 putative …
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Structural studies of dynein’s interaction with microtubules and herpesvirus
The dynein family is a group of minus-end directed microtubule motor proteins vital for long- range cytoplasmic cargo transport and ciliary beating. The dynein heavy chain consists of an N- terminal tail domain responsible for cargo binding and dimerization, and a C-terminal motor domain. In order …
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The regulation and role of glycoprotein C during herpesvirus pathogenesis
Submission original under an indefinite embargo labeled 'Open Access'. The submission was exported from vireo on 2022-11-11 without embargo terms
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Equine Herpesvirus Type 1: Filling Gaps Toward Improved Outbreak Management
Equine herpesvirus type 1 (EHV-1) is a common pathogen of horses that typically causes upper respiratory disease, however is also associated with late-term abortion, neonatal foal death and neurologic disease. Once a horse is infected, the virus concentrates to local lymphoid tissue, where it …
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Genetic divesity of Human Herpesvirus Type 8 in Northern South Africa
Background: Human herpesvirus type 8 (HHV-8), is an oncogenic virus responsible for causing all forms of Kaposi`s sarcoma (KS). HHV-8 prevalence varies globally, however, it is more prevalent in African countries, with South Africa having over 50% of HHV-8 infections. HHV-8 encodes a highly diverse …
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Bystander influence of nematode exposure on subsequent herpesvirus infections in vivo
… of these effects on susceptibility to subsequent herpesvirus infections in vivo. We show that prior N. brasiliensis infection enhanced control of acute respiratory murid gammaherpesvirus (MuHV-4) infection, with an increase in viral-specific CD8+ T cells in colonized lung tissue. Enhanced effector …
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The role of heterochromatin markers in lytic human herpesvirus egress and maturation
The human herpesviruses are large, double-stranded DNA viruses known for their persistent latent phase. Within the herpesvirus family there are 3 subfamilies; alphaherpesviruses, classified as such because of their more rapid replication and latency in neurons; betaherpesviruses, known for slow …
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ON THE NOSE: MUCOSAL IMMUNE RESPONSES DURING EQUINE HERPESVIRUS TYPE 1 INFECTION
… and mortality animal viruses, including equine herpesvirus type 1 (EHV-1). EHV-1 is endemic in horse populations worldwide, causing respiratory disease and sometimes results in abortion in pregnant mares and the neurological disease, equine herpesvirus myeloencephalopathy. A successful mucosal …
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Structural and functional characterisation of pUL21, an α-herpesvirus phosphatase adaptor protein
… virus 1 (HSV-1) is a very prevalent human herpesvirus that causes life-long infection and is known to dramatically remodel the cellular environment upon replication. This extensive manipulation is achieved using only a limited number of virus-encoded proteins, many of which possess numerous …
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Simultaneous cytomegalovirus and herpesvirus meningitis in an adolescent immunocompetent patient a case report
Antecedentes: la meningitis viral es una afección inflamatoria de las meninges que se manifiesta como neurológica. disfunción con signos clínicos variables, que van desde manifestaciones leves (como dolor de cabeza) hasta convulsiones e hipertensión intracraneal. La presentación clínica puede …
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The role of cellular signalling pathways and translation initiation factors in Herpesvirus infection
As obligate intracellular parasites, viruses rely on host cells to replicate. Hsv-1 is a large double stranded DNA virus which is the cause of common cold sores and corneal blindness in humans. The defining feature of HSV-1 is its ability to exist in two discrete states. During lytic infection, …
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Investigating the epidemiology of Terrapene herpesvirus 1 in freeranging eastern box turtle populations
Herpesviruses are ubiquitous, well described pathogens in captive chelonians worldwide, but their importance on free-ranging populations are less defined. In this thesis, a quantitative PCR was developed that detected a 58 base pair segment of the DNA polymerase gene segment of Terrapene …
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Characterization of the Interactions Between Kaposi’s Sarcoma-Associated Herpesvirus ORF57 and Its RNA Partners
Kaposi's sarcoma-associated herpesvirus (KSHV; HHV-8) is a human gammaherpesvirus and the etiological agent of Kaposi's sarcoma (KS), the most common AIDS-associated malignancy. Like all herpesviruses, KSHV has evolved mechanisms to modulate both host and viral gene expression. The essential and …
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