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Showing 1 to 2 of 2 for “"heritability estimation"”.

  1. Problems in Pedigrees and Phylogenies

    … problems within both settings. We begin with heritability estimation using pedigree data, with an ordinal outcome trait. We discuss the use of the threshold model for heritability estimation, exploring the consequences of model misspecification and sample size requirements under this model. …

    washington Repository record for Problems in Pedigrees and Phylogenies (opens in a new tab)

  2. Causal inference in integrative genomics: exploring de novo mutations and unravelling causal mechanisms via gene regulatory networks in developmental process

    … estimated Single Nucleotide Polymorphism (SNP) heritability of DNM count in offspring, which measures the relative contribution of genetic factors to the variance of the trait, in a Principal Component Analysis (PCA)-selected subset of the 100kGP cohort. To gain deeper insights, we separately …

    cambridge Repository record for Causal inference in integrative genomics: exploring de novo mutations and unravelling causal mechanisms via gene regulatory networks in developmental process (opens in a new tab)