Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 14 of 14 for “"hepatic function"”.
-
Effect of multiple doses of imidocarb dipropionate on renal and hepatic function of ponies
… was placed on the potential adverse effects on hepatic and renal function in this species. Serum bile acids and serum gamma glutamyltransferase activity were measured to evaluate the effect of this treatment regime on hepatic function. The diffuse hepatocellular necrosis and pronounced …
-
Lignocaine extraction ratio and clearance as an indicator of hypoxic hepatic injury : a study using the in situ and the isolated perfused pig liver
… has been found useful as an indicator of hepatic function in association with liver transplantation. It has been postulated that this might be due to the common effect of hypoxic damage on liver function and lignocaine metabolism. The aim of this work was to establish whether hepatic …
-
The effects of left hepatic vein ligation on hepatic circulation, function and microanatomy
… portography, and histologic assessment of hepatic tissue. The left hepatic vein was ligated in the chronic and acute dogs. The dogs had a ligature placed loosely around the left hepatic vein. Acute and control dogs were evaluated 24 hours postoperatively with the hematologic and biochemical …
-
Evaluation of dietary patterns influence on hepatic epigenetic gene modulation and dietary recommendations for the prevention of NAFLD to the general population
… to evaluate the influence of dietary patterns on hepatic epigenetic gene modulation and provide dietary recommendations for the prevention and management of NAFLD in the general population. Methods: A comprehensive screening and eligibility criteria were applied to identify relevant articles …
-
Efficacy of the Bromsulfophthalein (BSP) 30-Minute Retention Test for the Diagnosis of Hepatobiliary Disease in Dogs
… intravenous injection can be used to evaluate hepatic function. BSP retention of less than 5% 30 minutes after intravenous administration is considered normal in dogs. The BSP retention test fell out of favor due to perceived inaccuracy when compared with bile acid and ammonia testing and a …
-
Prenatal Programming of Hepatic Glucose and Cholesterol Regulation in Male Rat Offspring by Chronic Intermittent Hypoxia
… that CIH offspring have diminished regulation of hepatic gluconeogenic pathways by the Liver X Receptor (LXR), leading to increased expression of hepatic markers associated with gluconeogenesis and increased glucocorticoid signalling. Adult male CIH offspring were also hypercholesterolemic with …
-
The epithelial-mesenchymal transition of hepatocyte in liver cirrhosis
Liver cirrhosis is characterized by hepatic dysfunction with extensive accumulation of fibrous tissue in the liver. Even though the number of hepatocytes seems to be enough to maintain liver function, hepatic failure is one of the main causes of death in the patients with liver cirrhosis. The role …
-
From iPSCs to Engineered Heart and Liver Models: Modulating Genetic and Extracellular State for Maturity
… from significant limitations in structural and functional maturity. This dissertation integrates multi-omic profiling, genetic engineering, biomaterials-based strategies, and microfabrication to advance the fidelity and utility of iPSC-derived hepatic and cardiac models. For hepatic …
-
The Molecular Mechanism Of The Gwas Association Of The Slc22a1 Locus With Metabolic Traits
SLC22A1 is a hepatic plasma membrane transporter that transports a wide array of endogenous and xenobiotic molecules; however its impact on the physiology has been largely unexplored. Genome-wide association studies (GWASs) have revealed novel associations at the SLC22A1 locus for plasma …
-
The effect of acute alcohol exposure on hepatic oxidative stress and function: prevention by micronutrients
… the effect of acute ethanol administration on hepatic oxidative damage and apoptosis was examined using both an in vivo and in vitro approach; the effect of micronutrient supplementation prior and during ethanol exposure was also studied. The following studies were performed: (1) ethanol …
-
ENVIRONMENTAL CONTAMINANTS IN FARM AND WILD ANIMALS
… due to prolonged exposure and declining hepatic function. Significant differences in trace element concentrations were also observed between species, influenced by factors such as feeding behavior, body structure, and environmental exposure. The research underscoreed the importance of …
-
Trasmissione post-natale del citomegalovirus attraverso il latte materno al neonato VLBW
… infant to evaluate the complete blood count, the hepatic function and the C reactive protein. In addition, samples of fresh breast milk were processed weekly for CMV culture. A genetic analysis of virus variant was performed in the urine of the infected infants and in their mother’s milk to …
-
Comprehensive Assessment of Physiological, Biochemical, and Reproductive Parameters of Crossbred Goats in Response to Bee Pollen Supplementation
… the experiment. Blood samples were analyzed for hepatic enzyme activity, hormonal concentrations, and metabolic status. The statistical analysis for this study was conducted using the MIXED procedures of SAS software. Pens were considered the experimental unit for grouped variables, while …
-
Liver resection for hepatocellular and fibrolamellar carcinoma in a South African tertiary referral centre
… and in those with cirrhosis and well-preserved hepatic function. Despite advances in surgical techniques and perioperative care, hepatectomy remains a high-risk surgical procedure with complications occurring in up to 40% of resections. This adds a significant burden to individual patients by …