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Showing 1 to 12 of 12 for “"hepatic enzymes"”.

  1. Prizidilol : analytical methods and in vitro metabolism by hepatic enzymes

    Huang, Cheng-YiDivision of Clinical Pharmacology1984

    Two separate assays for prizidilol have been developed. One relies on separation by high performance liquid chromatography, and the other on separation by thin layer chromatography. Both of these methods have several advantages over the existing assay developed by JC Pearce for Smith Kline and …

    cape-town Repository record

  2. Deuterium isotope effects on in vitro dealkylation of 1,1-dimethylhydrazine and 1,1-dimethylnitrosamine via hepatic enzymes

    Sloane, Robert

    rit Repository record

  3. D-glucaric acid excretion: its positive association with gender, tobacco, caffeine, marijuana, and vegetarianism in humans

    Kyle, Elizabeth EllenVirginia Polytechnic Institute and State University1982

    … as a nonspecific measure of the induction of hepatic enzymes associated with drug metabolism in man. A survey of 124 nonmedicated men (18-56 years of age), who kept a 5-day food and beverage intake record and collected their total urinary output for the last three days of the five, was …

    vt Repository record

  4. Synthese des UDCA-7[beta]-N-Acetyl-D-glucosaminids und Stoffwechsel der Isoursodeoxycholsäure (IsoUDCA) beim Menschen

    Yildiz, YildizPublikationsserver der RWTH Aachen University2001

    … isomerised, probably both by intestinal and hepatic enzymes to yield UDCA, which becomes the major biliary compound.

    aachen Repository record

  5. Histone modification during the induction of tyrosine transaminase

    Graaff, G De VDepartment of Chemistry1972

    … which regulate the synthesis of specific enzymes in mammalian tissue, as well as for the role of hormones in this process". The in vivo administration of hormone initiates a chain of reactions which culminate in the increase of protein synthesis. Many hepatic enzymes are thus affected …

    cape-town Repository record

  6. The renal effects of nonsteroidal anti-inflammatory drugs (NSAIDS) in dogs with chronic kidney disease (CKD)

    Lomas, AmyKansas State University2013

    … blood pressure and renal parameters, as well as hepatic enzymes are recommended.

    ksu Repository record

  7. Studies of Folate Metabolism in Man and the Rat

    Saleh, Adly M.Aston University1981

    … not found in normal urine. The induction of the hepatic enzymes by phenobarbitone failed to increase the catabolic rate of folate. The possible mechanism of folate breakdown in the tissues has been elucidated to be a simple chemical oxidative cleavage of the C9- N10, bond of labile folate …

    aston Repository record

  8. Tetrachlorobiphenyl metabolism, toxicity, and regulation of cytochrome P50 expression in a marine teleost fish

    White, Renee D.Massachusetts Institute of Technology and Woods Hole Oceanographic Institution1994

    … elicited strong and sustained induction of hepatic CYP1A1 mRNA, protein content, and catalytic activity. A high TCB dose (5.0 mg/kg) elicited similar, strong induction of hepatic CYP1A1 mRNA, but not of CYP1A1 protein content or catalytic activity. This post-transcriptional "suppression" at …

    woods-hole Repository record

  9. Detoxificação mista do farelo de mamona e sua utilização na terminação de cordeiros

    Borja, Máikal SouzaUniversidade Federal da Bahia2015

    … weight and average daily gain. The levels of hepatic enzymes GGT, AST and ALT were not influenced by the inclusion of detoxified castor meal, just as the levels of albumin, cholesterol and triglycerides. Based on the evaluated results is possible to reduce the level of CaO to 10g / kg of …

    brazil-ufba Repository record

  10. Hepatic stellate cell heterogeneity and function during the hepatic regenerative response

    Kitto, LauraThe University of Edinburgh2023

    … the Western world1 and results in centrilobular hepatic necrosis. In non-severe cases the liver regenerates to normal microarchitecture and function. However, in severe APAP-induced ALF, transplantation remains the only curative treatment. Hepatic stellate cells (HSCs) play a central role during …

    edinburgh Repository record

  11. Hepatic CYP1A enzymes in fish as a biomarker of water pollution

    Chirananon, JunjaruneLincoln University1997

    … in the aquatic environment. Induction of hepatic cytochrome P450 1A (CYP1A) enzymes in fish have been used as a biomarker to detect exposure to PAH and to a certain extent PCB-like compounds. In the present study, Chinook salmon (Oncorynchus tschawytscha) were used as an animal model (i) …

    lincoln Repository record

  12. Regulation of Human Renal Drug Transporters by Inflammatory Cytokines and Pregnancy-related Hormones in Primary Proximal Tubular Epithelial Cells

    Tsang, Yik Pui2026

    … physiology and modulating drug-metabolizing enzymes and transporters in eliminating organs. Regulation of hepatic enzymes in these states is relatively well described. However, the magnitude, direction, and mechanisms of renal transporter regulation remain poorly defined. This is despite …

    washington Repository record