Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 15 of 15 for “"hemocompatibility"”.
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Structured surfaces for hemocompatibility
The rise of micro- and nano-technologies has brought to light intriguing examples of scale-driven performance in a diverse array of fields. The quest to create highly hydrophobic surfaces is one such field. The application of this new generation of hydrophobic surfaces, however, has not received …
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Hemocompatibility of polymeric materials for blood-contacting applications
Hemocompatibility of a biomaterial plays a vital role in the overall success of the biomaterial in the body. Every implanted biomaterial tends to cause an immune response by the host tissue. The intensity of said response depends on many factors, including the properties of the material itself. In …
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The determination of hemocompatibility of a geometrically-altered poly(dimethylsiloxane) surface
Bio- and hemocompatibility are some of the driving forces behind medical device creation and materials science in this day and age. An experimental study was performed to test whether a geometrically altered surface of Poly(dimethylsiloxane), or PDMS, was found to be more or less hemocompatible …
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Surface Modification of Commonly used Polymer Plastics for Increased Hemocompatibility in Medical Equipment
Exposure of synthetic materials to body fluids may result in undesirable protein−material interactions, this can potentially trigger deleterious biological processes such as thrombosis. The result is increased chances of heart attack, stroke or other cardiovascular complication after extravascular …
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Hemocompatible polymer thin films fabricated by Electrostatic Self-Assembly (ESA)
… and pH during the process. Three preliminary hemocompatibility testes were performed to evaluate the hemocompatibility of the coatings. Platelet adhesion study showed the thin films inhibited platelet adhesion. All thin films were able to inhibit coagulation and were less cytotoxic. The …
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Polycaprolactone nanowire surfaces as interfaces for cardiovascular applications
… only dependent on tissue integration but also hemocompatibility (interaction of material with blood components), a property that depends on the surface of the material. A thorough understanding of the interaction of cardiovascular cells and whole blood and its components with the material …
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In Vitro and In Silico Study of Deposition on Textured Biomaterials: Towards Biofunctionalization of Ventricular Cannula
… To induce endothelialization and improve hemocompatibility, LVAD manufacturers adopted powder sintering in multiple contemporary LVADs. Despite the wide adoption of sintered titanium, clinical outcomes over the past several decades have been highly variable, ranging from neointima to …
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Fabrication of microfluidic devices for artificial respiration
… of detrimental pressure gradients. The hemocompatibility analysis demonstrated that the network construct showed acceptable levels of hemolysis rate (< 8%) and thrombus formation.
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The wettability of biomaterials determines the protein adsorption and the cellular responses
… of the strategies for improving the materials hemocompatibility, which is believed to be the most ideal solution for making truly blood-compatible materials. Since at physiological conditions proteins such as FNG and fibronectin (FN) are the usual extracellular matrix (ECM) for endothelial …
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Improving blood compatibility of surfaces using tanfloc and carboxymethyl-kappa-carrageenan polyelectrolyte multilayers
… coatings. The second aim investigates the hemocompatibility of TAN and carboxymethyl-kappa-carrageenan (CMKC) PEMs on titanium nanotube arrays (TiNT). Results demonstrated superior performance of CMKC compared to heparin (HEP) in reducing platelet adhesion, activation, and whole-blood …
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Development of an integrated microfluidic platform for oxygen sensing and delivery
… microfluidic capillary network with respect to hemocompatibility, mass transfer, and dissolved oxygen detection. Microfluidic capillary devices were fabricated from silicone rubber using multilayer soft lithography to create dense 2D networks of bifurcating channels. To quantify the …
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Differenziamento macrofagico: gli effetti dei polimeri sintetici
… due to their good mechanical properties and hemocompatibility (Zdrahala R.J. and Zdrahala I.J., 1999). In the biocompatibility evaluation of these synthetic polymers, that is important for its potential use in clinical applications, a fundamental aspect is the knowledge of the polymers …
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Designing a safe dendronised polymeric nanocarrier for hydrophobic drugs or gene delivery in cancer therapy
… could efficiently condense DNA with excellent hemocompatibility and high gene transfection in Hela and Hek293T cells. Thus, this work offers an effective strategy of designing a non-viral system and the P-PLLA, P(Lac)-PLLA, PSS-PLLA and P-OGPLLL nanocarriers serve as a reliable drug/gene …