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Showing 1 to 1 of 1 for “"heme and iron metabolism"”.
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Biological Clocks, Inflammation, and Multiorgan Damage In Sickle Cell Disease
… role of S1PRs in SCD by utilizing pharmacologic and genetic tools. To determine the role of S1P-S1PRs signaling in SCD, I treated humanized Berkeley sickle mice (Berkeley HBS mice), with FTY720, a US Food and Drug Administration (FDA) approved drug. FTY720 can be phosphorylated by SphK1 thus …