Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 4 of 4 for “"hedgehog signaling pathways"”.
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MOLECULAR CHARACTERIZATION OF THE PUTATIVE NUCLEOTIDE- BINDING AND HYDROLYZING ACTIVITIES OF THE ELLIS VAN CREVELD (EVC) PROTEIN
… positively regulates the Sonic and Indian hedgehog signaling pathways by promoting downstream processes after activation of the smoothened receptor (Smo), by the hedgehog proteins. Bioinformatic analysis revealed the presence of several structural motifs in EVC sequences including P-loop, …
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Molecular Classification of Basal Cell Carcinoma of Skin by Gene Expression Profiling
… signature with the activation of Wnt and Hedgehog signaling pathways, which were well known key features of BCC. By contrast, the SCC-like BCC was enriched with immune-response genes and oxidative stress-related genes. Network analysis revealed the PLAU/PLAUR as a key regulator of SCC-like …
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Genetic Profiling in Soft Tissue Sarcoma
… to STS. The studies provide clues to the genetic pathways involved in STS development and identify profiles linked to diagnosis and prognosis. The results from Study I that concerns intratumor versus intertumor heterogeneity of gene expression profiles in malignant fibrous histiocytoma (MFH) and …
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The Role and Immunogenicity of CBFA2T3-GLIS2 in Pediatric Acute Megakaryoblastic Leukemia
… and CtBP1 and induces upregulation of oncogenic signaling pathways including Hedgehog, JAK/STAT, Notch, and RUNX. Loss of NHR2 disrupted ETO association with the fusion, decreased fusion homodimerization, and abrogated leukemogenesis in vivo. I observed downregulation of JAK/STAT, Notch, and …