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Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.

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Showing 1 to 20 of 161 for “"heavy chain"”.

  1. Immunoglobulin Heavy Chain Expression In Human B-Lineage Cells.

    Kerr, William Garrow

    uab Repository record

  2. Analysis Of The Regulation Of Mu Heavy Chain Synthesis And Expression (Immunoglobulin).

    Hendershot, Linda Marie

    uab Repository record

  3. Pre-BCR signaling amplifies antibody diversity by activating secondary immunoglobulin heavy chain gene rearrangement

    Khadour, AhmadUniversität Ulm

    ulm-diss Repository record

  4. Cellular And Molecular Aspects Of Immunoglobulin Isotype Switching (Epstein-Barr Virus, Heavy Chain Genes).

    Webb, Carol Frances

    uab Repository record

  5. Transdermal delivery of heavy chain only antibody binding domains using hydrogel-forming microarray patches

    Hutton, AaronQueen's University Belfast2022

    … mAbs. This new era of biotechnology incorporates heavy chain only antibodies (HCAbs) such as Nanobody® molecules and VNARs, derived from camelids and sharks, respectively. Owing to their small size (~13 kDa) and reduced complexity, they are less expensive to produce than mAbs. Furthermore, their …

    qu-belfast Repository record

  6. Gene Expression of myosin heavy chain isoforms in pigs of different genetic groups and ages

    Ribeiro, André Mauric FrossardUniversidade Federal de Viçosa2015

    … to evaluate gene expression pattern of myosin heavy chain isoforms in pigs of three different genetic groups at four ages. 48 castrated males of Piau, Commercial and Crossbred (Piau X Commercial) genetic group, slaughtered at birth, 56, 112 and 156 days. Longissimus dorsi muscle samples were …

    brazil-ufv Repository record

  7. Spatial organisation of the immunoglobulin heavy chain locus and inter-chromosomal gene networks driving B cell development

    Mielczarek, OlgaUniversity of Cambridge2018

    … in the bone marrow from the immunoglobulin heavy chain (Igh) and light chain (Igk and Igl) loci. The mouse Igh is a large (~3Mb) multigene locus that contains 195 variable (V), 10 diversity (D) and 4 joining (J) genes that undergo developmentally regulated V(D)J recombination to produce the …

    cambridge Repository record

  8. Metabolic profile of myosin heavy chain-based fiber types in the rat soleus after spinal cord transection

    Otis, Jeffrey ScottVirginia Tech2000

    … and types of contractile proteins (myosin heavy chain, MHC) that are expressed. Research has shown that decreased neuromuscular activation following spinal cord transection (ST) results in adaptations in the physiological characteristics of paralyzed muscles, including atrophy and an …

    vt Repository record

  9. The Role Of Immunoglobulin In Heavy Chain Binding Protein In The Posttranslational Processing And Assembly Of Immunoglobulin Molecules.

    Bole, David Giles

    uab Repository record

  10. Expression der Isoformen des „Myosin Heavy Chain“ (neonatal, developmental und fast) sowie N-CAM bei myogenen und neuromuskulären Erkrankungen

    Walther, Michael

    … in den letzten Jahren auch die Gruppe der Myosin Heavy Chains (MHCs), Hauptbestandteil der dicken Filamente im Sarkomer. <br>Mittels Immunhistochemie konnten bislang sieben Isoformen dieser Proteinfamilie entdeckt werden, die im Skelettmuskel vorkommen. Dies sind vier „fast“ Isoformen (Weydert et …

    freiburg-diss Repository record

  11. Difference between myosin light and heavy chain isoforms patterns in fast- and slow-twitch skeletal muscle: effect of endurance training

    Alev, Karin2005

    tartu

  12. Mutational and functional analyses of the dynein heavy chain indicate the existence of an apical-sistal transport cycle in cells

    Sivagurunathan, SenthilkumarUniversity of Missouri--Kansas City2012

    … multiprotein motor complex composed of heavy chains, intermediate chains, light intermediate chains, and light chains. The heavy chains form the force producing motor entity of the dynein complex and the rest of the components are involved in linking dynein to cargoes. The heavy chain …

    umkc Repository record

  13. Evidence that ARNT plays a role in the regulation of the immunoglobulin heavy chain enhancer and identification of a putative ARNT ligand

    Yavrom, Sheena2018

    … nuclear translocator) at the IgH (immunoglobulin heavy chain) enhancer. We were able to determine that ARNT appears to partially down-regulate activation at the IgH enhancer by Pan-1 in transient transfection assays by cotransfection of the multimerized murine form of the IgH enhancer elements …

    u-pacific Repository record

  14. Inter-alpha-trypsin inhibitor heavy chain H4 as a diagnostic and prognostic indicator in patients with hepatitis B virus-associated hepatocellular carcinoma

    노, 충균2014

    OBJECTIVES: Inter-alpha-trypsin inhibitor heavy chain H4 (ITIH4) is associated with various diseases. We evaluated the diagnostic and prognostic significance of serum ITIH4 levels in healthy controls and patients with chronic hepatitis B (CHB), hepatitis B virus (HBV)-related liver cirrhosis, and …

    ajou Repository record

  15. A study of the role of glycogen in skeletal muscle performance and of myosin heavy chain isoform expression in amphibian skeletal muscle using the toad Bufo marinus

    Nguyen, Long ThanhVictoria University of Technology2000

    The overall aim of this study was to contribute knowledge to two areas of inquiry in muscle research: one concerned with the molecular mechanism(s) underlying the positive correlation between intracellular glycogen content and skeletal muscle performance and the other with the MHC isoform …

    vu-aus Repository record

  16. Construction and mutagenesis of an anti-insulin single chain Fv (scFv) using protein engineering techniques: Identification of peptide mimotopes which inhibit scFv-insulin binding.

    Lake, Douglas Fletcher.The University of Arizona.1993

    … cloned independently as V(H) and V(k). A single chain Fv (scFv) was constructed using a polymerase chain reaction (PCR) assembly technique from the anti-insulin V(H) and V(k). The scFv demonstrated similar, but not identical binding properties to the parental anti-insulin antibody. Binding of …

    arizona-thes Repository record

  17. Involvement of a specific ubiquitin ligase in the assembly of the dynein motor in the filamentous fungus Neurospora crassa

    Elsenpeter, Ryan LeeUniversity of Missouri--Kansas City2012

    … subunits and accessory proteins, including heavy chains, light chains, intermediate chains, light intermediate chains, and dynactin to form a motor complex of several megadaltons. The last two thirds of the dynein heavy chains contain the main motor unit required for force production, while …

    umkc Repository record

  18. Thermodynamic Evidence That Ganglioside-Mediated Insertion Of Botulinum A Into The Cholinergic Nerve Ending May Precede Endocytosis And Acidification: A Langmuir Film Study

    Strongin, Bradley Adam2007

    … the conditions under which BoNT type A heavy chain would bind and/or insert into mica supported dipalmitoylphosphatidylcholine (DPPC) lipid bilayers. As an alternate technique, DPPC/GT1b or total ganglioside extract (80:20) monolayers of a Langmuir Blodgett (LB) Trough were adapted to be …

    byu Repository record

  19. The Arrangement of the Disulfide Bonds in a γG Immunoglobulin Molecule

    Gall, William Einar

    … component light (molecular weight 22,500) and heavy (molecular weight 51,600) chains were isolated in high yield by gel filtration after reduction and alkylation under mild conditions. Amino terminal analyses and the amino acid compositions of the native molecule and its chains indicated that …

    rockefeller Repository record

  20. The Role of RNA Helicase RHAU in Immunoglobulin Class Switch Recombination

    Jean Guillaume, Sabine2022

    … guide RNAs to target AID to the immunoglobulin heavy chain switch (S) regions in the DNA for CSR. Sequence alignment revealed homology between the AID G4 binding domain and the RNA helicase associated with AU-rich element (RHAU) specific motif (RSM), which allows RHAU binding to G4 RNAs and …

    cuny Repository record

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