Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 44 for “"heart transplantation"”.
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Donor heart preservation for heart transplantation
Heart transplantation has enjoyed a spectacular success over the past 25 years. Prior to 1980 less than 350 operations were carried out with an overall one year survival of less than 60%. In 1995 more than 3,000 transplants were performed with a one year survival of 83%. However, growth and …
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Germinal centre autoantibody responses following heart transplantation
… of humoral autoimmunity following organ transplantation is increasingly recognised, but of uncertain significance. I address the key question whether autoimmunity contributes independently to chronic graft rejection. In a MHC class II-mismatched murine model, I show that antinuclear …
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Heart transplantation--is there a relation between experience and outcome?
Thesis (Ph. D.)--Massachusetts Institute of Technology, Whitaker College of Health Sciences and Technology, 1991.
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Role of peroxisome proliferator-activated receptors in mechanisms of rejection in heart transplantation
… PPAR agonists in parenchymal rejection (PR) and transplantation-associated arteriosclerosis (TxAA). Four different PPAR agonists (fenofibrate and Wy14643 for PPARα; BRL69453 and 15-deoxy-[delta]¹⁴̹⁶ Prostaglandin-J₂ for PPAR[gamma]) in an in vitro model of the alloresponse all demonstrated a …
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In-Silico design and verification of an extracorporeal normothermic cardiac perfusion system for use during heart transplantation procedures
Heart transplantation relies on effective donor organ preservation to ensure successful graft viability. Since the first human heart transplant in 1967 by Christiaan Barnard, organ preservation techniques have evolved from static cold storage with cardioplegic arrest to continuous blood perfusion, …
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In-Silico design and verification of an extracorporeal normothermic cardiac perfusion system for use during heart transplantation procedures
Heart transplantation relies on effective donor organ preservation to ensure successful graft viability. Since the first human heart transplant in 1967 by Christiaan Barnard, organ preservation techniques have evolved from static cold storage with cardioplegic arrest to continuous blood perfusion, …
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Magnetic Resonance Imaging in Paediatric Coronary Vasculopathy
… leading cause of late death for children after heart transplantation. It often presents late due to lack of ischaemic symptoms from the denervated allograft and it is difficult to detect using conventional angiography. A non-invasive diagnostic tool would be invaluable for the early detection …
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Treatment approaches to chronic decompensated heart failure
Heart failure remains, to this day, a clinical challenge for both patients and clinicians. For stage A and B patients, lifestyle changes, healthier diets, risk factors control, and comorbidities management are recommended. In stage C, aside from the general management in stages A and B are …
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A Study of Craniofacial Growth in Infant Heart Transplant Recipients Receiving Cyclosporine
… that has found widespread application in organ transplantation. However, a few studies have implicated cyclosporine as adversely affecting craniofacial growth in the pediatric population. The purpose of this study was to evaluate the possible untoward effects of cyclosporine long-term on …
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A 23-year retrospective review of heart transplant donor and recipient referrals to Groote Schuur hospital between 1997 and 2019
Background. Heart transplantation in South Africa faces numerous challenges related to organ scarcity and unequal access to advanced heart therapy. There is an urgent need to analyse the current transplant referral pathway to optimise equitable access to transplantation. Objectives. To provide an …
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Liver transplantation for transthyretin amyloidosis: experience of a single center in Italy
Liver transplantation is the only definitive treatment for transthyretin amyloidosis, with an excellent 5-year survival in endemic countries where the Met30 mutation is predominant. We report our experience of liver transplantation for transthyretin amyloidosis. We reviewed the clinical records of …
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Hearts and minds : how do people experience and psychologically recover from traumatic cardiac treatment-related events?
… of potentially traumatic cardiac treatments: heart transplantation and implantable cardioverter defibrillators (ICD). It was hoped that such an endeavour would yield novel insights into these treatments that might facilitate the development of pertinent theory and psychotherapeutic approaches …
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A Continued Investigation of Craniofacial Growth in Infant Heart Transplant Recipients Receiving Cyclosporine
… and now has a widespread application in organ transplantation. Several studies, however, have implicated cyclosporine as adversely affecting craniofacial growth in the pediatric population. <sup>16,18 </sup>The purpose of this follow-up study was to continue to evaluate the possible untoward …
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Assessing Risk For Right Heart Failure After Left Ventricular Assist Device Implantation
… negatively impacted by the diagnosis of Advanced Heart Failure. Financial burden, repeated hospitalizations, and declining quality of life account for poor outcomes. Implantation of a left ventricular assist device (LVAD) has offered the promise of improved financial, clinical, and functional …
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A Continued Investigation of Craniofacial Growth in Infant Heart Transplant Recipients Receiving Cyclosporine
… that has found widespread application in organ transplantation. A couple of studies, however, have implicated cyclosporine as adversely affecting craniofacial growth in the pediatric population. The purpose of this follow-up study was to continue to evaluate the possible untoward effects of …
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Family and Child Psychosocial Functioning of Infant Heart Transplant Recipients
<p>With the advancement of medical procedures, heart transplantation has become a viable alternative for infants born with congenital or acquired heart disease. Although these children are thought to experience much improvement in their overall physical functioning post-transplantation, the …
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