Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 84 for “"hazard ratio"”.
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Time to surgery and thyroid cancer survival in the United States
… A survival analysis was performed using the Cox- hazard ratio as well as Kaplan-Meier curves. RESULTS: Preliminary results detail the fact that delaying surgeries past 180 days for patients led to decreased survival over a course of 5, 10, and 15 years as was determined by the use of Kaplan Meyer …
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Statistical Inference for the Treatment Effect in Cancer Clinical Trials
… trial with a time to an event as the endpoint, hazard ratio is a popular measure for the relative difference between treatment groups. Most current statistical inference procedures for hazard ratio rely on the proportional hazard assumption, which may not be applicable to practice when it does …
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Renal tubular secretion in chronic kidney disease: description, determinants, and outcomes
… disease are currently assessed by glomerular filtration rate and urinary albumin excretion. Other kidney functions, such as proximal tubular secretion, are not typically quantified. Tubular secretion is capable of clearing metabolites from the blood more efficiently than filtration, suggesting …
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Prostate-specific Antigen Nadir and Time to Prostate-specific Antigen Nadir Following Maximal Androgen Blockade Independently Predict the Prognosis in Patients with Metastatic Prostate Cancer
… TTN had the worst progression-free survival (hazard ratio 14.098, p<0.001) and cancer-specific survival (hazard ratio 14.050, p<0.001) compared to those with lower PSA nadir and longer TTN. CONCLUSIONS: Our results suggest that higher PSA nadir level and shorter TTN following MAB are …
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Probabilistic Time-to-Event Modeling Approaches for Risk Profiling
… time-to-event models that account for calibration and uncertainty, while predicting accurate absolute event times. Specifically, we introduce an adversarial nonparametric model for estimating matched time-to-event distributions for probabilistically concentrated and accurate predictions. We …
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Emotionales Befinden, Krankheitsverarbeitung und Überlebenszeit bei Bronchialkarzinompatienten
… mit einer kürzeren Überlebenszeit einhergeht(hazard ratio 1.75, 95% confidence interval 1.04-2.93, p = 0.034). Der körperliche Leistungszustand (Karnofsky-Index) stellte ebenfalls einen unabhängigen Prädiktor für die Überlebenszeit dar. Diese Ergebnisse stimmen mit denjenigen der Vorstudie von …
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The Effect of Obesity on Disability and Mortality in Mexican Older Adults
… index (BMI) were collected. Results: The lowest hazard ratio (HR) for disability was at BMI of 25 to <30 (HR=0.97; 95% confidence interval [CI], 0.85-1.12). The lowest HR for mortality were seen among participants with BMIs 25 to <30 (HR=0.85; 95% CI, 075-0.97), 30 to <35 (HR=0.86; 95 % CI, …
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Antihyperglycemic Adherence and Risk of Stroke among Type II diabetes mellitus: A Population-based Retrospective Cohort Study
… costs. Objective: To examine whether long-term hazard among type 2 diabetes patients is reduced by high adherence to antidiabetic medication. </p> <p> Methods: An all-medical care claims merged database of all patients with a diabetes diagnosis 2000-2009 was used. Newly diagnosed diabetes …
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Novel imaging and blood biomarkers in acute aortic syndrome
… condition. It is characterised by medial degeneration which is beyond the resolution of conventional anatomical imaging. Here, we investigate 18F-sodium fluoride positron emission tomography and computed tomography (PET/CT) and circulating biomarkers in patients with acute aortic syndrome. …
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Comparative analysis of cervical disease progression in HIV positive women receiving ART and those not receiving ART in Cape Town, South Africa, from 2002 to 2011
… for SIL. A Cox model was built to determine the hazard for SIL development. This hazard was adjusted for ART status, CD4 count and age. CD4 count was treated as a time varying covariate. Women older than 40 years had a showed a 58% reduction in the progression of cervical disease from normal to …
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Bayesian Hierarchical Frailty Models for Heterogeneity in Risk
… with the Cox model, which assumes proportional hazards. When heterogeneity in risk is present, the assumption of proportionality is violated and the Cox model's population-averaged estimate of the hazard ratio can underestimate the effect for an individual. In this dissertation, we develop …
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Desarrollo de alteraciones electrocardiográficas y eventos clínicos tras el recambio de válvula aórtica transcatéter: técnica de superposición de senos coronarios frente a técnica tradicional.
… riesgos proporcionales de Cox para calcular el Hazard Ratio.
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Association of GLP-1 Receptor Agonist Use with Kidney and Cardiovascular Outcomes in Stable Kidney Transplant Recipients
… reduced risk for all-cause mortality (adjusted hazard ratio [aHR]: 0.45; 95% confidence interval [CI]: 0.32-0.62) and MAKE (aHR: 0.69; 95% CI: 0.58-0.81), but no significant difference for MACE (aHR: 0.84; 95% CI: 0.67-1.05). In addition, users show increased risk for irritable bowel syndrome …
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Modeling Recurrent Metastatic Events
… of 547 genes. We identify 1,130 somatic alterations significantly associated with organotropism, including 171 associations with brain metastases. We train a penalized predictive model that can accurately identify individuals at high risk for metastases to specific organ sites in held out …
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Statins and Risk of Alzheimer Disease: A Systematic Review and Meta-Analysis
… to 17 years. From the random-effects model, the hazard ratio for Alzheimer disease in statin users as compared with nonusers was 0.76 (95% confidence interval, 0.55 to 1.06).</p><p>Conclusions: The random-effects model predicted that statin use is associated with an average reduction in risk of …
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Inter-alpha-trypsin inhibitor heavy chain H4 as a diagnostic and prognostic indicator in patients with hepatitis B virus-associated hepatocellular carcinoma
… independently associated with overall survival (hazard ratio 5.894, 95% confidence interval 1.373–25.300, P = 0.017). A Kaplan-Meier survival analysis showed significantly worse survival among HCC patients with both low ITIH4 (<80 DU) and a large tumor size compared to that among other HCC …
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The South-South partnership to provide cardiac surgery: The Namibian Children Heart Project
… associated with a 5% increased risk of death (Hazard Ratio 1.05, 95% confidence interval: 1.02-1.08, p=0.001). Follow-up was complete in 151 (78%) patients over seven years. Conclusions: Despite the challenges associated with a cardiac programme referring patients for intervention to a …
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Building improved risk stratification models for patients post non ST-segment elevation acute coronary syndrome using ambulatory ECG data
… and left ventricular ejection fraction (adjusted hazard ratio for one-year death (95% Cl): 5.25 (1.42, 21.2)). This model is unique in its simplicity, as it relies on simple logistic regression with only three features, which are automatically computed and easily interpreted. Our findings …
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Incidence rate of fluoroquinolone resistant gram-negative rod bacteremia among allogeneic hematopoietic cell transplant patients during an era of levofloxacin prophylaxis
… using Poisson regression. Cox proportional hazards regression was used to compare 30-day mortality between patients with FQ-resistant and those with FQ-sensitive GNR bacteremia. <bold>Results:</bold> Of the 2306 patients included in this cohort, 283 (12.3%) had GNR bacteremia. The IRs of GNR …
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Prognostic factors in soft tissue sarcoma. Tissue microarray for immunostaining, the importance of whole-tumor sections and time-dependence.
… factors for metastasis vascular invasion, hazard ratio (HR) 3.5, tumor necrosis (HR 2.8), and tumor growth pattern (HR 3.2), and the latter also correlated with local recurrence (LR). In comparison, histological malignancy grade, tumor size, and depth were not of independent prognostic …
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