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Showing 1 to 3 of 3 for “"haplotype-based association"”.
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Haplotype-Based Association Studies: Approaches to Current Challenges
<p>Haplotype-based association studies have greatly aided researchers in their attempts to map genes. However, current designs of haplotype-based association studies lead to several challenges from a statistical perspective. To reduce the number of variants, some researchers have employed …
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Studies at the hemochromatosis (HFE) locus : gene conversions, haplotypes, and association analysis
Haplotype-based association studies offer an exciting potential methodology for the identification of genes that contribute to complex traits. There is thus great interest in understanding the biological forces that shape haplotypes. We have studied a well-characterized genetic locus surrounding …
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Linkage disequilibrium and haplotype block patterns in popcorn populations
Linkage disequilibrium (LD) and haplotype blocks have been a preliminary and powerful knowledge for genomic investigates in humans, animals and plants. We aimed to describe the LD measures, D’ and r 2 , and to characterize haplotype block patterns in popcorn populations (synthetic and breeding …