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Showing 1 to 1 of 1 for “"hairpin whole genome bisulfite"”.
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Mapping Bisulfite-Treated Short DNA Reads
… Upon PCR amplification, the bisulfite treatment of DNA converts unmethylated cytosine to thymine, while 5-methylcytosine, 5-hydroxymethylcytosine, and other bases remain unchanged. The resulting sequences can be mapped to a reference genome; however, this can be challenging …