Global ETD Search
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Showing 1 to 3 of 3 for “"hair cell differentiation"”.
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Adenoviral Mediated Gene Delivery to Human Umbilical Cord Mesenchymal Stromal Cells for Inner Ear Hair Cell Differentiation
… results from degeneration of inner ear sensory hair cells and auditory neurons in the cochlea. In recent years, there has been an increasing interest in gene delivery to mesenchymal stem cells. Gene delivery approaches to stem cells can provide an opportunity to engineer a variety of specialized …
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Promotion of Hair Cell Fate by Atoh1 and MicroRNA-183 Family
Hair cells are the mechanoreceptors responsible for hearing and balance in the inner ear. Multiple factors cause hair cell loss including aging, noise exposure and genetic predisposition. A barrier to hearing restoration after hair cell loss is the inability of mammalian auditory hair cells to …
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Decoding Dynamic Gene Regulation in Hair Cell Development and Regeneration
… between genes and their proteins during the differentiation of specialized cells such as mechanosensory hair cells in vertebrates' inner ears and fishes' lateral lines requires an accurate description of the time-lagged relationships between transcription factors and their target genes. Here …