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Showing 1 to 1 of 1 for “"hESC gastruloids"”.
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The Role and Control of WNT Signalling in an HESC Model of Human Primitive Streak
… I used an in vitro human embryonic stem cell (hESC) micropatterned "gastruloid" system. I first showed that in the human PS there is a conserved BMP → WNT→ NODAL signalling initiation hierarchy, and that WNT is necessary and sufficient for PS formation. Next, I found that structured …