Global ETD Search
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Showing 1 to 1 of 1 for “"hDot1L"”.
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Identification of a Functional Hotspot on Ubiquitin Required for Stimulation of Methyltransferase Activity on Chromatin
… of the human H3K79 methyltransferase, hDot1L, we developed a strategy for the site-specific chemical ligation of ubiquitin to preassembled mononucleosomes to greatly expedite structure activity studies of ubiquitin in a nucleosome context. Accordingly, we synthesized a library of …