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Showing 1 to 1 of 1 for “"hBRE1A/B complex"”.

  1. The Role of Histone H2B Ubiquitylation and its Related Factors in Transcriptional Regulation in Mammalian Cells

    … of a functional human homologue, the hBRE1A/B complex, of the yeast BRE1 E3 ubiquitin ligase. hBRE1A, which forms a complex with hBRE1B, specifically increases the global level of H2B ubiquitylation at lysine 120 and enhances activator dependent transcription in vivo. An extensive …

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