Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"gut-to-brain"”.
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From Gut to Brain - αSynuclein pathology spreading in a new transgenic mouse model
… Parkinson’s disease (PD) represent a challenge to contemporary society. The increase in life expectancy and the lack of therapies addressing the disease cause make these disorders a high burden to patients, caretakers and society in general. Aggregation of αSynuclein (αSyn) and presence of …
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The microbiome-gut-brain axis in preclinical alpha-synuclein models of Parkinson's disease
… nervous systems and is characterised by motor and non-motor symptoms. The primary pathological features of PD are the degeneration of the nigrostriatal pathway in the brain, causing motor dysfunction, and the build-up of α-synuclein protein fibrils throughout several brain regions. Many PD …
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Gut microbes and brain function
The gut-brain-microbiota axis comprises an extensive communication network between the brain, the gut, and the microbiota residing there. If the composition or the diversity of the gut microbiota is impaired, this can have negative consequences for host health and has been associated with disorders …
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Interactions Between Microbial, Neuronal, and Immune Cells in the Digestive System
… faces the unique challenge of remaining tolerant to harmless or beneficial diet- and microbederived stimuli, while simultaneously protecting against pathogen invasion. To tackle these challenges, the intestine houses both the body's largest immune compartment, as well as a vast neuronal …