Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 215 for “"gut microbiome"”.
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Engineering the gut microbiome of honey bees
… use. These bees house a simple, conserved gut microbiome that is important for their health. Can we use this gut microbiome to protect bees in new ways? Synthetic biology combines recombinant DNA technology and rational design principles to redesign biological processes. Microbiome …
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Evolutionary dynamics of the human gut microbiome
The composite members of the human gut microbiome encounter a myriad of selective pressures from the host environment and other microbial members in the ecosystem. Understanding the evolutionary dynamics of microbial species in the gut microbiome requires sequencing information that differentiates …
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Investigating the lignocellulolytic gut microbiome of huhu grubs
… it is likely that microbes present in the gut assist in degrading lignocellulose to release energy rich sugars. This process is considered the rate limiting step in the utilisation of woody material in biofuel production. To better understand the gut consortium present while feeding on the …
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Effects of 5��-Dihydrotestosterone (DHT) on Mouse Gut Microbiome– A Study of Sex Differences and Hormonal Effects on Gut Microbiome Composition
… have placed a higher significance on the role of gut microbiome in T1D pathogenesis. Furthermore, diabetic mouse models have shown higher incidence of T1D in females compared to males, attributed to the differences in gut microbial community structure. Interestingly, female mouse models elicit …
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The Influence of Diet on the Mammalian Gut Microbiome
<p>The mammalian gut is residence to a large microbial community whose collective set of millions of genes: microbiome) encodes a vast array of functions, including many that process dietary components. Few tools are available to change the microbiome's properties to promote host health because the …
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Gut Microbiome Dysbiosis Exacerbates Malaria Severity in Ugandan Children
… fully known, but murine studies implicate the gut microbiome. It remains unknown if gut microbiota contributes to SM pathogenesis in children. To address this knowledge gap, we sequenced the gut bacteria populations in stool samples from Ugandan children <5 years-old with SM and community …
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The impact of microgravity conditions on human gut microbiome
The human gut microbiome plays a fundamental role in maintaining overall health by regulating metabolism, immune function, and neurological processes. Disruptions to its balance can lead to various health complications. Space exploration introduces unique environmental challenges, particularly …
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Engineering the human gut microbiome through personalized dietary interventions
… composition and metabolic output of the human gut microbiota have been implicated in many diseases: from inflammatory bowel disease, colorectal cancer, and diarrheal diseases to metabolic syndromes like diabetes. Treatment of these diseases will likely require targeted therapeutic interventions …
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Dietary Manipulation of Metabolic Function in the Human Gut Microbiome
<p>The human gut microbiome is increasingly recognized as having a causal or contributing role in a wide variety of diseases. While mechanisms by which the microbiome contributes to or triggers disease processes are myriad, short-chain fatty acid (SCFA) production has been found to be a powerful …
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Ecological and Anthropogenic Influences on a Sentinel Species' Gut Microbiome
… are implications on the nonhuman primate gut microbiome. Wild Argentine black and gold howler monkeys (<em>Alouatta caraya</em>) are listed as “least concern” with a population that is decreasing. Despite their propensity to occupy habitats with varying degrees of degradation and …
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Characterization of the Swine Gut Microbiome Dynamics, Culturomics and Probiotics
… pathogens and other hazards. In pigs, the gut microbiota community assembled postnatal plays a very important role in the development of multiple physiologic aspects, such as development of the gastrointestinal tract, nutrient exchange, immune defense against foreign pathogens and growth …
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Understanding the role of phages in the mammalian gut microbiome
A healthy gut microbiome supports a stable microbial community that regulates immune responses, defends against pathogens, maintains gut barrier integrity, and modulates metabolic processes. Disruptions of the balanced microbial community, followed by effects on host health, often called dysbiosis, …
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THE BROWN BEAR GUT MICROBIOME: A NOVEL TOOL FOR CONSERVATION & MANAGEMENT
<p>Gut microbiomes (GMBs), complex communities of microorganisms inhabiting the gastrointestinal tracts of their hosts, perform countless micro-ecosystem services such as facilitating energy uptake and modulating immune responses. While scientists increasingly recognize the role GMBs play in host …
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The impact of dietary components on gut microbiome modulation and health
The human gut microbiome plays a critical role in maintaining overall health, influencing key physiological processes such as digestion, immune function, and behaviour. A deeper understanding of the complex interactions between the gut microbiome, diet, and disease is essential for advancing …
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Exploring the gut microbiome: metaproteome analysis of HIV-exposed uninfected infants
… to disease and have weaker immune responses. The gut microbiome plays a pivotal role in human health by aiding in metabolism, nutrient availability and immune development and function. The mucosal immune system and microbiome work in synergy to maintain host immunity and balance for optimal host …
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Structural characterization of glycyl radical enzymes in the human gut microbiome
… bacteria play important roles in the human gut microbiome and have dedicated chemical pathways for growth in the absence of oxygen. Glycyl radical enzymes (GREs) use an oxygen-sensitive glycyl radical cofactor to perform challenging, radical-based chemistry. Generation of this cofactor …
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Effects of the antibiotic tetracycline on the honey bee gut microbiome
… microbial communities, also known as microbiomes, are essential to the health of their hosts, and disturbance of these communities can negatively impact host fitness. The honey bee gut microbiome is a relatively simple host-associated community that makes an excellent model system for …
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SEX-DEPENDENT GUT MICROBIOME DIFFERENCES IN A TRANSGENIC MOUSE MODEL OF AUTISM
… Disorder (ASD). Changes in the diversity of the gut flora, and co-occurring gastrointestinal pathologies, have been consistently noted in studies of individuals with ASD. A number of mechanisms exist through which sAPPα overexpression may exert an influence on the initial development of the gut …
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COMMUNITY STRUCTURES OF GUT MICROBIOME UNDER DIFFERENT DIETS IN ANGUS BEEF CATTLE
… regions, hosts a unique and diverse microbiome that aids feed fermentation, digestion, and absorption. We hypothesize that compositions of diets can influence microbiomes and further affect the production of VFA and the composition of bile acids in beef cattle. We used rectum …
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