Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 13 of 13 for “"growth and remodeling"”.
-
MECHANICALLY MEDIATED GROWTH AND REMODELING OF COLLECTING LYMPHATIC VESSELS
… as immune disorders, infection, cancer, obesity, and cardiovascular disease; regarding the latter, lymphatic dysfunction may exacerbate edema in myocardial infarction (MI) and chronic heart failure. Secondary lymphedema is a progressive and debilitating disease characterized by fluid retention and …
-
Building Patient-Specific Models of the Heart to Study Cardiac Growth and Remodeling
Cardiac growth and remodeling (G&R) are intricate processes that occur in response to various physiological and pathological conditions to maintain the optimal function of the heart. These processes involve complex molecular, cellular, and structural alterations that influence the size, shape, and …
-
The Roles of Relaxin, Estrogen and Progesterone on Growth and Remodeling of the Cervix and Mammary Glands in the Gilt
… described relaxin-induced changes in physical and biochemical properties of the cervix that occur during the last third of the 115-day gestation period in the gilt. Histological changes in the cervix that occur between days 80 and 110 of pregnancy and the effects of relaxin on those changes …
-
Microfabrication Approaches for Understanding the Role of Vascular Mechanics in Progressive Diseases
… from long-term alteration of vessel structure and function. The underlying mechanisms that lead to pathologic changes in the vasculature are largely unclear, especially in progressive diseases of the cerebral vessels. With the growing prevelance of blast traumatic brain injury in modern …
-
Non-Enzymatic Activity Of The Alpha Tubulin Acetyltransferase Alpha-Tat1 Differentially Alters The Stability Of Dynamic And Stable Microtubules
… on an underlying network of both long-lived and dynamic microtubules that provide structural stability for the boutons while also allowing for their growth and remodeling. However, a molecular-scale mechanism that explains how neurons appropriately balance these two microtubule populations …
-
Design and use of an environmental control platform for studying vascular cell function in three-dimensional scaffolds
Endothelial and smooth muscle cells are the core of the vascular system. Vessels are created and repaired through the processes of angiogenesis and arteriogenesis. Endothelial cells are the initial cells that migrate and proliferate during the process, followed by smooth muscle cell movement and …
-
Factors affecting bone cell growth and differentiation under differing culture conditions
… osteoblasts is an important part of the bone growth and remodeling process. This process can be exploited to help solve the problem of bone wound healing. Because of problems with bone grafts, implantation of biodegradable 3D scaffolds seeded with MSCs has been suggested. However, differences …
-
Poroelastic Finite Element Analysis of a Heterogeneous Articular Cartilage Explant Under Dynamic Compression in ABAQUS
… been made between the relative fluid velocity and stimulation of</p> <p>glycosaminoglycan synthesis. A contour plot of the model shows the relative fluid</p> <p>velocity during compression exceeds a trigger value of 0.25 μm/s at the radial</p> <p>periphery. Dynamic UCC biochemical results have …
-
Transcriptional response to spatial learning and foraging in honey bees: molecular bases for adult neuroplasticity
… enable persistent neuroplasticity in the adult and aging brain. In many species, some types of neuroplasticity typically decrease with age. Honey bees and other social hymenopterans, however, exhibit a reinstatement of structural plasticity in association with flight and foraging behavior. Adult …
-
Unraveling the Role of EphA4 in Immune-Mediated Arteriogenesis After Ischemic Stroke
… remain dormant due to their small diameters and relatively low flow velocity. LMCs serve as vascular redundancies that retrogradely re-supply blood to help salvage the penumbra following cerebral vascular occlusion. Their outward growth or remodeling (arteriogenesis) is essential for …
-
The role of fibroblast growth factor-2 (FGF2) in vascular remodeling and adaptation
… was to test the hypothesis that fibroblast growth factor-2 (FGF2) is required during diseased-related vascular growth and remodeling in the adult organism. Given previous research, it is generally assumed that FGF2 is an important regulator of vessel growth during various pathophysiological …
-
Bioinformatic identification and characterization of cytokinetic regulators in Mtb
A fundamental lack of understanding of Mtb regulation during latent tuberculosis infections (LTBI), which comprises the vast majority of tuberculosis cases, has hindered global eradication efforts. To elucidate mechanisms associated with transition to the non-replicating persistent (NRP) state …
-
Regulation of Intestinal Development and Function in Early-Life Pigs
… plasticity allows for rapid structural and functional adaptions in response to external stimuli. The early postnatal phase is a critical developmental window, during which diet transitions and stress can have lasting effects on overall health and productivity. Attenuated growth …