Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 10 of 10 for “"grignard reaction"”.
-
The synthesis and properties of 4-substituted pyrrolidine-2,3-Diones
… position is examined in suitable compounds by reaction with hydrazine and ethylene diamine. The 4-benzylidene, 4-carbethoxy and 4-cyano compounds are of particular interest since they might be expected to facilitate the formation of the enol at C3. The spectroscopic features and reactions of …
-
Synthesis of Biologically Relevant Sphingolipid Analogues
… D-ascorbic acid, a common food preservative. Key reaction in this synthetic approach was a fully regioselective epoxide opening with lithium 1,3-dithiane. In addition, a fully stereoselective Grignard reaction gave access to D-ribo-N-homophytoceramide.
-
Total synthesis of naturally occurring glycosylated tetramic acids
… glycosylation followed by a C-2 epimerisation reaction of the sugar moiety, a HWE olefination, an aminolysis reaction to install the L-alanine residue, followed by a Lacey-Dieckman cyclisation. The 7S stereocenter was established using a rhodium based homogeneous catalyst and applying a …
-
Borafluorenes and polyborafluorenes boron doped varients of fluorene
… synthetically via lithium halogen exchange and Grignard reaction pathways. Once incorporated, the borafluorene could be polymerized or undergo further functionalization via Yamamoto and Stille coupling reactions. This incorporation of boron into a conjugated system imparted Lewis acidic and …
-
The Synthesis and Characterization of Some Ir(III) Dicationic Complexes
… [IrH(COD)(PMe3)3][Cl]2o2HCl was prepared by the reaction between [Ir(COD)(PMe3)3]Cl and HCl gas in methylene chloride. The product precipitated from the solution and is soluble in polar solvents such as water, acetonitrile, and acetone. [IrH(COD)(PMe3)3][Cl]2o2HCl undergoes reaction in water to …
-
Amphiphile Phosphane für die Anwendung in neuen polaren Medien
… on imidazolium-groups with n-BuLi and subsequent reaction with Ph2PCl has been elaborated. Additional phosphines of this type have been synthesized by metathesis reaction or by selective N-quarternisation of a corresponding neutral phosphine with Et3OPF6. The synthesis of phosphines containing …
-
Selected reactions of some cyclic sulfoxides
… Sulfoxide <u>1</u> was reacted with various Grignard reagents and shown to undergo a substitution reaction at the α-carbon atoms. Predominant reaction occurred at position-5 of <u>1</u> and binary sulfide mixtures composed of 2-substituted-4-methyl- and …
-
Discovery of Novel Tubulin Inhibitors and Selective Survivin Inhibitors for Advanced Melanoma and Total Synthesis of Bioactive 20S-hydroxyvitamin D3
… synthetic method involved Suzuki coupling and Grignard reactions to modify the 3,4,5-TMP moiety and to produce target compounds in gram-scale. Among the eight analogues synthesized, the one containing an unique 3-methoxybenzo[4,5]-dioxene moiety had the strongest antiproliferative activity …
-
Derivatisierungsreaktionen von Cinchona-Alkaloiden und eine Cinchona-Alkaloid-katalysierte asymmetrische Synthese von 2,5-Diarylphopholanen
… reagents leads to 2´-alkylated products. The reaction with Grignard reagents leads to new 4´-substituted cinchona alkaloid derived aminals via conjugate addition. Direct core-alkylation by means of organometallic reagents is an easy way to access structural analogues of the cinchona alkaloids. …