Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"granuloma model"”.
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Anti-platelet aggregation activity of melaleuca bracteata var.revolution gold derived betulinic acid and its derivatives
… was investigated using the cotton pellet-induced granuloma model in rats. The homogenates from the granuloma tissues were used to determine the effect of the test compounds on catalase (CAT) and superoxide dismutase (SOD) activities. The in vitro effect of the triterpenes on cyclooxygenase COX-1 …
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Physiologically-Based Pharmacokinetic (PBPK) Modeling for the Preclinical Development of Spectinamide Antibiotics
… frequency, and routes of administration in mouse models of Mtb infection and in healthy animals. Characterizing the disposition of a compound in the tissues of interest is important in understanding the pharmacology of novel antibiotic agents. TB is primarily a pulmonary disease, but …
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Some bioactivity of triterpenes from stem bark of protorhus longifolia and their derivatives
… bleeding time assay and cotton pellet-induced granuloma model in Sprague-Dawley rats, respectively. The effect of the triterpenes on the expression of heat shock protein 70 (Hsp70) and their anti-protein aggregation activity using malate dehydrogenase (MDH) aggregation suppression assay were …