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Showing 1 to 2 of 2 for “"granule cell precursors"”.

  1. Distinct DNA Damage Signaling in the Brain Distinguishes ATLD, NBS, and ATR-Seckel Syndrome

    … a situation of extreme stress under which a cell must either be capable of repairing the lesions in order to continue replication or succumb to death. Not surprisingly, deficiencies in DNA repair genes often lead to human diseases frequently associated with genomic instability, cancer …

    tenn-hsc Repository record for Distinct DNA Damage Signaling in the Brain Distinguishes ATLD, NBS, and ATR-Seckel Syndrome (opens in a new tab)

  2. Investigating the Fate of Pre-neoplastic Cells in a Mouse Model of Medulloblastoma

    … presumed to be a transition during which normal cells undergo malignant transformation. However, the link between the pre-neoplastic cells and end-stage disease has never been formally established. To investigate the fate of such cells, the patched (ptc) mutant mouse, a model for the brain tumor …

    duke Repository record for Investigating the Fate of Pre-neoplastic Cells in a Mouse Model of Medulloblastoma (opens in a new tab)