Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 271 for “"granule"”.
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Carbachol-Induced Pigment Granule Dispersion
… the RPE aids in light adaptation through pigment granule movements. In the bright light, pigment granules are dispersed into the long apical processes thereby shielding rods from excessive light. The opposite occurs in dark conditions; pigment granules are aggregated into the cell body of the RPE …
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Vibration-induced densification of granule materials
Physical experiments as well as discrete element simulations of vibration are carried out. The use of different amplitudes and frequencies are applied in the experiments to facilitate the observation of densification trends with mono-disperse acrylic spheres and multi-disperse polyethylene pellets. …
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Excitotoxicity, oxidative stress and neuroprotection in cerebellar granule neurones
… disease. This study used cultures of cerebellar granule neurones as a model for investigation of these processes, considering both their pharmacological and molecular aspects. Another important part of the study was the development and investigation of a mode of neuroprotection which was …
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Investigating xanthine oxidase toxicity models in cultured cerebellar granule neurons
… For this project, primary cultures of cerebellar granule neurons (CGNs) were used. In the beginning, some problems were encountered with CGNs. The main problem was the immediate damage induced to the neurons (including those in the control groups) at the intervention/experiments day (i.e. day 8 or …
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Studies on the Granule-Moving System of Melanocytes of Fundulus Heteroclitus
<p>Pigment granules in melanocytes of Fundulus heteroclitus exhibit both local movements and long distance intracellular migrations in response to hormones. These movements have been studied and a theory of the granule moving system has been proposed: The granules are in a structured continuum …
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The Role of [beta]2-Syntrophin Phosphorylation in Secretory Granule Exocytosis
The trafficking of insulin secretory granules(SGs) of pancreatic b-cells is a tightly controlled complex network. Increasing evidence indicates that the cortical actin cytoskeleton modulates the mobility and exocytosis of SGs,yet the mechanisms anchoring SGs to the cytoskeleton is not completely …
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The Recovery of Protein from Egg Yolk Protein Extraction Granule Byproduct
… yolk separates into two distinct fractions—granules and plasma. It is becoming increasingly popular in the industry to remove the plasma fraction of the egg yolk to use for its livetins, particularly immunoglobulin Y, leaving behind a granule by-product (“yellow cake”). Previous research has …
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Postmitotic Dynamics in Chromatin Modification and Regulatory Topology Underlie Cerebellar Granule Maturation
… find that the postnatal maturation of cerebellar granule neurons (CGNs) requires dynamic changes in the genomic distribution of histone H3 lysine 27 trimethylation (H3K27me3), demonstrating a causal function for this chromatin modification in gene regulation beyond its canonical role in cell fate …
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Production, characterisation and uses of antibodies to the insulin secretory granule membrane
… antigens present in the insulin secretory granule membrane. These were to be used in a study of the composition, biosynthesis and turnover of the secretory granule membrane.
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In-situ Study of Single Pharmaceutical Granule Drying using Synchrotron X-ray Imaging
The drying process of wetted granules using common methods such as fluidized bed drying is a key unit operation in the pharmaceutical tableting industry. To ensure homogeneity and product quality for a wide range of formulations in the final tableted product, the monitoring of changes to an …
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Cerebellar granule cell-specific deletion of the AMPA receptor subunit GluR-D gene
Ionotrope Glutamatrezeptoren spielen eine entscheidende Rolle bei physiologischen und pathophysiologischen Prozessen im Gehirn. Die Rezeptoren werden in drei Untergruppen eingeteilt aufgrund ihrer pharmakologischen Eigenschaften und ihrer Sequenzähnlichkeit. Diese sind die …
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Studies on the mechanism of polyhydroxybutyrate (PHB) granule formation in Ralstonia eutropha H16/
… produced by bacteria in the form of insoluble granules for carbon storage. Insights into the mechanisms of granule formation are important for improving commercial PHB production and engineering new alternatives to petroleum-based plastics. Using both biochemical and imaging methods, we …
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GRANULATION OF ULTRA-FINE POWDERS: EXAMINATION OF GRANULE MICROSTRUCTURE, CONSOLIDATION BEHAVIOR, AND POWDER FEEDING
… Behavior of Ultra-Fine Powders: Examination of Granule Microstructure, Consolidation Behavior, and Powder Feeding. Major Professor: James Litster
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Death, survival, and morphological development of hippocampal granule cells born in an inflammatory environment
The brain continues to form new neurons throughout life. This process of adult neurogenesis has been thoroughly documented in several species including birds, rodents and humans. Adult neurogenesis is not a global process, but is confined to two subcompartments of the brain; the subventricular zone …
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On the transmission properties of synapses made between granule cells and cerebellar Purkinje cells
… The ascending axon (AA) segment of the granule cell axon forms synapses with PCs as well as the PF segment. PPF and fluctuation analysis of EPSCs in rat PCs confirmed that the release sites of AA synapses have a greater probability of transmitter release than PF synapses. Furthermore, AA …
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