Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 2 of 2 for “"gradient hydrogel"”.
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Hydrogel platform to investigate the coordinated impact of niche signals on hematopoietic stem cell fate
… In this thesis, I describe the development of a gradient hydrogel platform that enables co-culture of HSCs with multiple niche components, namely exogenous niche cells, extracellular matrix proteins, and matrix-tethered biomolecular signals. Gradients in microenvironmental signals are common …
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Multigradient hydrogels to decode extrinsic regulation of hematopoietic stem cell fate
Hematopoiesis is a physiological process responsible for the generation of all the blood and immune cells of the body. The cells responsible for this process are the hematopoietic stem cells (HSCs), primarily located within the bone marrow. They are housed in specific microenvironments (niches) …