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Showing 1 to 20 of 262 for “"glycoproteins"”.
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Computational Studies of Glycan Conformations in Glycoproteins
… preference between glycans in solution and in glycoproteins has been examined. Using molecular dynamics (MD) simulations, the conformational preference of N-glycan pentassacharide in solution is exhaustively studied. Surprisingly, the conformational distribution is dominated by a single major …
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Electrophoretic Determination of Glycoproteins in Human Gingiva
… oral inflammation were fractionated as well. The glycoproteins were analyzed using a polyacrylamide gel electrophoretic technique employing an E.C. apparatus. The conditions included a 5% gel matrix, tris buffer pH 8.6, y 8.4 x 10~3 with respect to the salt, 5°C for 3 hours. The gels were stained …
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Purification of glycoproteins from herpes simplex virus
The aim of this work was to purify type-specific glycoproteins from herpes simplex virus type 1 (HSV-1) and type 2 (HSV-2) for diagnostic use. The most likely candidate for a type-specific glycoprotein of HSV-1 is glycoprotein C (gC), although it has recently been shown to contain some type-common …
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Structure determination of glycoproteins by mass spectrometry
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Chemistry, 1996.
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Analysis of glycans and glycoproteins by mass spectrometry
… these glycan structures affect the function of glycoproteins on a molecular level, it is important to characterize the glycans in a glycosylation site-specific manner. The feasibility of site-specific analysis is demonstrated here by characterizing glycans of follicle stimulating hormone in two …
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Biology of the envelope glycoproteins of sheep betaretroviruses
Retroviruses possess several biological features that differentiate them from all other infectious agents. The obligatory integration step of the retrovirus genome into the host genome has allowed these viruses to associate, modulate and alter the biology of the cell with a variety of unique …
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Vitamin A and glycoproteins of rat corneal epithelium
Previous work from this laboratory has shown that the uptake of labeled precursors into a single specific glycopeptide in the rat intestinal mucosa was depressed significantly in vitamin A deficiency (De Luca et al ., 1970). A very similar pattern to the intestinal glycopeptide pattern was obtained …
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The effect of vitamin A on plasma glycoproteins
… D-glucosamine and D-mannose into the plasma glycoproteins was studied in vitamin A-deficient rats by comparison with the plasma of normal pair-fed controls. Preliminary studies indicated that peak incorporation (specific activity) was reached three hours after intraperitoneal injection with …
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The nucleotide binding domains of multidrug resistance-p-glycoproteins
Bibliography: leaves 116-128.
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Characterization of Metastasis-Associated Cell Surface Glycoproteins in Prostate Cancer
… site distal to the primary tumors. Cell surface glycoproteins play pivotal roles as recognition molecules in a range of cell communication and adhesion events. Aberrant cell surface glycosylation has been reported in various cancers including PCa, and strongly correlated with prognosis and …
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Effects of magnesium deficiency on urinary glycoproteins in the rat
… effects of magnesium deprivation on the urinary glycoproteins of adult and grow.ing rats. The glycoproteins were to be isolated in 0.58 M Na.Cl, the isolation technique for Tamm-Horsfall glycoprotein. Quantitative excretion was measured as ɣ hexose/rat/day. Qualitative analyses were reported as …
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Axonal Transport of Glycoproteins and Glycolipids in the Goldfish Optic System
… extensively. However, the axonal transport of glycoproteins labeled with radioactive sugars had not previously been examined. In the experiments reported here, [<sup>3</sup>H]D-glucosamine and [<sup>3</sup>H]L-fucose were injected into the goldfish eye. Both sugars are incorporated into …
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Factors affecting transduction efficiency of pseudotyped viral vectors incorporating alphaviral glycoproteins
<p>The genome of an organism has the complete set of biochemical instructions required for sustenance of life. Mutations or abnormalities in this genome lead to genetic disorders. Currently available therapeutic options mostly focus on treating the symptoms, but not curing them. Gene therapy …
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The expression and regulation of pregnancy-specific glycoproteins in the mouse
Pregnancy-Specific Glycoproteins (PSG) are the most abundant fetally expressed proteins in the maternal bloodstream at term. This multigene family are immunoglobulin superfamily members and are predominantly expressed in the syncytiotrophoblast of human placenta and in giant cells and …
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MS-Based Chemical Proteomics Studies of Extracellular Glycoproteins: Identification, Quantification, and Dynamics
… and dynamics. Despite their importance, surface glycoproteins cannot be easily studied due to their low abundance, glycan heterogeneity, and surface specificity, surface glycoproteins cannot be easily studied. This thesis work is focused on the study of extracellular glycoproteins, including …
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Biochemical Characterization of Hydroxyproline-rich Glycoproteins in the Arabidopsis Root Cell Wall
… member of the plant cell wall hydroxyprolinerich glycoproteins (HRGPs) superfamily and presumably functions by self-assembling into a scaffold that forms a covalently cross-linked wall network. Here, the self-assembly of extensins from Arabidopsis, tomato, tobacco and maize and extensin analogs …
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Antifreeze Glycoproteins of Two Unrelated Polar Fishes: Gene Structure, Organization and Evolution
The AFGPs of the northern cods are also encoded by a family of polyprotein genes in which multiple AFGP coding sequences linked in tandem by small cleavable spacers Args or Arg-Ala-Ala-Arg's. However, the northern cod AFGP genes show no sequence identity with trypsinogen gene, indicating …
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