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Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 105 for “"glycolic acid"”.
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Novel Biodegradable Poly (Glycolic Acid) Dual-Layer Packaging System Using Spray Coating
… paper substrate spray-coated with a poly(glycolic acid) (PGA) outer layer is designed to enhance barrier performance. The approach involves spray coating CNF onto the paper substrate to effectively fill surface pores, followed by an additional spray coating of PGA to create a dense, …
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Phase Inversion Dynamics of Polylactic Glycolic Acid Solutions Related to Biopharmaceutical Drug Delivery
… the protein particle was densified with stearic acid and placed in a slow phase-inverting depot formulation. Particle densification can potentially be used with any protein or highly soluble drug agent, unlike other techniques that are protein specific. Taking advantage of the effects of low …
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Bioactive Poly(Lactic-co-Glycolic Acid)-Calcium Phosphate Scaffolds for Bone Tissue Regeneration
… regeneration. Biocompatible poly(lactic-co-glycolic acid) (PLGA) has been processed through a number of techniques to create porous 3D architectures. Hydroxyapatite (HAP) and tricalcium phosphate have been used in conjunction with polymer scaffolds due to their osteoconductivity and …
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The effects of glycolic acid and Dow latex 464 (Saran) on the strength and microstructure of neat cement paste
Thesis (Civ. E.)--Massachusetts Institute of Technology, Dept. of Civil Engineering, 1967.
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Designing and characterizing the plant-based chitosan-modified poly (lactic-co-glycolic acid) nanoparticles for salmonella and e. coli-induced gastroenteritis
… plant-based chitosan-modified poly (lactic-co-glycolic acid) nanoparticles for Salmonella and E. coli-induced gastroenteritis. Medicinal plants used as an alternative treatment for gastrointestinal infection were collected from Iikokola village in the Omusati region in Namibia. Organic and …
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Profiling of urinary metabolites in human pregnancy
Maternal urinary metabolites (organic acids and steroids) in human pregnancy were profiled by gas-chromatographic methods. Urine specimens were collected from pregnant women at two time intervals in gestation (12½-15½ weeks and 24½-27½ weeks). A group of nonpregnant women was also investigated. The …
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Preparation and characterization of poly lactic-co-glycolic nanoparticles encapsulated with gentamicin for drug delivery applications
… industry. In this work, poly-lactic-co-glycolic acid (PLGA) was used in nanoparticle synthesis due to its biodegradability, biocompatibility, and nontoxicity. For this work, gentamicin was loaded into the PLGA nanoparticles as an antibiotic because it is a broad-spectrum antibiotic …
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The effect of pH and dissolved organic carbon on the growth kinetics of Ac. cupricumulans JTC3 and L. ferriphilum HT pertinent to the BIOX® process
… archaea including the iron-oxidizer, Acidiplasma cupricumulans JTC3. In this study, the effect of physicochemical factors, such as pH and temperature, and the presence of dissolved organic carbon on the growth and ferrous iron oxidation kinetics of these two microorganisms were …
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DRUG ELUTING TISSUE ENGINEERED VASCULAR GRAFTS
… formation, and a microfiber poly(lactic-co-glycolic acid) (PLGA) inner layer loaded with an antiproliferative agent. PCL typically takes 1-2 years to degenerate, where as PLGA takes approximately weeks to months depending on the ratio of Poly Lactic Acid (PLA) to Poly Glycolic Acid (PGA) …
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Biodegradable, Liquid-Filled, Spherical Capsules With Pre-Determined Burst Times
A biodegradable poly(lactic acid-co-glycolic acid) (PLGA) capsule is presented in a spherical geometry, which exploits the principle of osmosis as an internal program to achieve a delayed-burst release of its load. The capsule burst lag-time is accurately predicted by modeling the rate of water …
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Osteoblast Response to Zirconia-Hybridized Pyrophosphate Stabilized Amorphous Calcium Phosphate
… polyesters, such as poly(DL-lactic-co-glycolic acid) (PLGA), have been used to fabricate porous bone scaffolds to support bone tissue development. These scaffolds allow for cell seeding, attachment, growth and extracellular matrix production in vitro and are replaced by new bone tissue …
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3D Printing Of A Biocompatible Scaffold And A Real-Time Imaging Window For Monitoring Rat Spinal Cord Regeneration
… polycaprolactone (PCL), poly(lactic-co-glycolic acid) (PLGA), and silicone- were evaluated to balance mechanical compliance with biological performance. While PLGA exhibited favorable mechanical characteristics, PCL demonstrated superior cytocompatibility, cellular attachment, and …
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Lamination of a biodegradable polymeric microchip
… to a 200- [mu]m thick poly(D,L-lactic-co-glycolic acid) 2A membrane, and the film-laminated microchip was shown to release 14C-dextran within a 40-day period. The final proposed design was based on Design 2, which demonstrated more potential as a future means of drug delivery.
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Poly ([beta]-amino ester)s as pH sensitive biomaterials for microparticulate genetic vaccine delivery
… vaccination is the administration of nucleic acids to induce cellular expression of antigens, leading to an immune response. Unlike traditional vaccines, this technology has tremendous potential for treating or preventing diseases such as HIV, malaria, and cancer. However, this potential is …
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Developing Low Fouling Peptides and Zwitterionic Materials for Biomedical Applications
… found in nature. The peptide sequences glutamic acid/lysine (EK) and asparagine (N) were identified as displaying resistance to nonspecific protein adsorption. The low fouling sequence EK was further applied to several biomedical applications including multifunctional self-assembled monolayers on …
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Biorubber (PGS) : evaluation of a novel biodegradable elastomer
… vivo biocompatibility to PLGA, poly(L-lactic-co-glycolic acid), a widely used biodegradable polymer. PGS has been tested for use as nerve guide material and to fabricate artificial capillary networks for tissue engineering applications, both yielding promising results. Currently, the PGS research …
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A Novel Technique for Fabricating Aligned Nanofibers by Using Solution Electrospinning
… system at 1.0 ml/h. As polymer, poly(lactic-co-glycolic acid) (PLGA 50/50) was dissolved in hexafluoro-2-propanol (TCI). Collected nanofibers were examined under Scanning Electron Microscope (SEM). Nanofibers were 0.7 µm in diameter and 1.5 cm in length. Besides creating aligned nanofibers by …
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