Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 36 for “"glycaemia"”.
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Determination of phytochemicals in vegetable juices and their effects on postprandial glycaemia
High fruit and vegetable intake correlates well with positive health outcomes and reduced rates of chronic diseases such as cardiovascular diseases, type 2 diabetes, cancers, neurological decline and metabolic diseases. Bioactive phytochemicals such as polyphenols, carotenoids, vitamins, minerals …
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Investigating the effectiveness of New Zealand Blackcurrant extract to modulate postprandial glycaemia in overweight/obese individuals
… is sustained periods of postprandial hyperglycaemia. Current epidemiological evidence has suggested that habitual anthocyanin intake is linked to lower T2DM risk. The aim of this thesis was to investigate whether anthocyanin-rich New Zealand blackcurrant (NZBC) extract could be an effective …
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Relationships of gastric emptying with glycaemia, insulin secretion and the incretin effect in health and type 2 diabetes
… This has profound implications for control of glycaemia in diabetes, as even minor variations in the rate of entry of nutrients into the small intestine may be associated with substantial changes in postprandial glycaemic and insulinaemic responses. The incretin hormones, GIP and GLP-1, located …
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A novel nutritional approach to the management of type 2 diabetes: effects of nutritional preloads on postprandial blood glucose and gastric emptying in type 2 diabetes mellitus
… or in combination before a meal, on postprandial glycaemia, GLP-1, insulin, and gastric emptying 4) The evaluation of the effects of 12 weeks’ treatment with a whey/guar preload on gastric emptying, postprandial glycaemia, and glycated haemoglobin (HbA1c), in type 2 diabetes. It is well …
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The role of polyphenols on sugar release from carbohydrate rich foods, and the consequent impact on metabolic risk factors associated with type 2 diabetes
… extract, on starch digestion and on markers of glycaemia. Throughout an in vitro digestion procedure, green tea and all of the polyphenol rich extracts were found to reduce starch digestion from white bread, and this effect was dose specific. These same doses of green tea extract and baobab …
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Optimising the management of new-onset prediabetes/diabetes after acute pancreatitis
… seen over 24 months of follow-up: normal-stable glycaemia, moderate-stable glycaemia, and high-increasing glycaemia. A high glycaemic lability index at baseline increased the odds of taking the high-increasing trajectory by 13-fold. Elevated insulin levels at baseline significantly increased the …
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La glycémie maternelle en grossesse et la leptine dans le sang de cordon : des déterminants de l’adiposité dans l’enfance
… are overweight. Exposure to maternal hyperglycaemia complicated or not by gestational diabetes (GDM), maternal adiposity and excessive gestational weight gain (GWG) are factors predisposing children to develop obesity beyond the traditional risk factors such as genetics. This is the fetal …
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Defining the molecular, genetic and transcriptomic mechanisms underlying the variation in glycation gap between individuals
… fructosamine estimations in the assessment of glycaemia has frequently been observed and is referred to as the glycation gap (G-gap). This could be explained by the higher activity of the fructosamine-3-kinase (FN3K) deglycating enzyme in the negative G-gap group (patients with lower than …
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The effect of metformin on vascular function and AMP-activated protein kinase activation in Type 2 diabetes
… in the treatment of Type 2 diabetes to improve glycaemia but the precise site, mode and extent of their actions remain uncertain. For example, in the United Kingdom Prospective Diabetes Study (UKPDS), metformin treatment reduced the incidence of myocardial infarction by 39% in comparison with …
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Dietary approaches to managing diabetes in pregnancy
… after delivery. Suboptimal management of hyperglycaemia increases the risk of pre-eclampsia, preterm birth, excessive fetal growth, birth injuries, neonatal hypoglycaemia, and long-term future risk of type 2 diabetes. Diet and lifestyle modifications are the cornerstone of diabetes management, …
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The role of a deglycating enzyme ‘fructosamine-3-kinase’ in diabetes and COPD
… so that they tend to have lower average glycaemia than actually the case, while others with low rates of deglycation appear to have higher than actual glycaemia (known as the glycation gap, G-gap). The G-gap has been reported to be associated with alteration of diabetic complications …
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Beneficial effects of Cinnamomum burmannii in the treatment of diabetes mellitus
… body weight with higher dose in diabetic rats. Glycaemia was also decreased (p<0.05) at week 3. In the heart, ACE with both doses had significant effect (p<0.05) in normal and diabetic rats, namely, increases in Mg2+, K+, Ca2+ and Fe2+ levels. In the liver, kidneyand pancreas, cinnamon treatment …
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Glucose metabolism in the critically ill.
Hyperglycaemia occurs frequently in the critically ill, even in those without a history of diabetes, and is associated with adverse outcomes. While the gastrointestinal tract is pivotal in the regulation of glucose metabolism in health and diabetes, this relationship had not been explored in the …
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Optimisation of the Investigation of Antibody-Mediated Dysglycaemia
… patients with diabetes and unexplained labile glycaemia. IA, and plasma insulin before and after PEG precipitation, were determined. Three groups were identified: the first were ‘negative’ for actionable IA; the second had demonstrable IAs of potential significance that warrant further study; …
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Aspects of Abnormal Glucose Regulation in Various Manifestations of Coronary Artery Disease
… 1. To evaluate the association between admission glycaemia and future disturbance in glucose regulation, and mortality in patients with acute coronary syndrome (ACS). 2. To describe the association between diabetes and outcome after in-hospital cardiac arrest. 3. To evaluate the prevalence and the …
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The effects of polyphenol rich chocolate on cardiovascular risk and glycaemic control in type 2 diabetes mellitus
… with T2DM with an induced transient hyperglycaemia caused by a 75g oral glucose load (n=10). The final clinical trial was a three-arm randomised double-blinded parallel study aimed to investigate the effects over a 12-week period of milk chocolate enriched with flavanols in an attempt to …
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Investigation of potential intervention targets to improve insulin action: a therapeutic approach
… In vivo studies were undertaken to investigate glycaemia, insulinaemia, satiety and body weight in streptozotocin-induced diabetic mice and obese (ob/ob) mice. Leptin acutely altered insulin action in skeletal muscle cells via the short form of the leptin receptor. This direct action of leptin …
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Effects of exercise, with and without an associated energy deficit, on postprandial metabolism and appetite regulation
… period postprandial lipaemia, insulinaemia and glycaemia, total ghrelin and acylated ghrelin concentrations, pulse wave velocity and energy substrate utilisation were determined. Subjective ratings of appetite and food palatability and energy and macronutrient intakes at an ad libitum buffet …
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Metabolic complications resulting from the use of antiretroviral therapy in HIV-infected patients
… a number of metabolic complications, such as dysglycaemia, insulin resistance and lipodystrophy. Lipodystrophy is characterised by an increase in trunk fat (lipohypertrophy) and/or a decrease in limb fat (lipoatrophy). This thesis investigates the metabolic complications associated with ART, and …
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Innovative food design to support a healthier diet – exploring the effects of dietary fibre enrichment on functional characteristics, physiological and microbiome effects, and consumer acceptance of staple foods
… fibre-rich diet including developed products on glycaemia, energy intake, satiety, and the gut microbiome. Methods: Chapters 2-3 present comprehensive reviews of fibre-based nutritional strategies and critically evaluate the evidence supporting the use of isolated fibres, including resistant …
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