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Showing 1 to 1 of 1 for “"gly-phe β-naphthylamide"”.
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Ca2+ signalling between the endoplasmic reticulum and lysosomes
… the exchange of Ca2+ occurs. The dipeptide, glycyl-L-phenylalanine 2-naphthylamide (L-GPN), is much used to disrupt lysosomes and release Ca2+ from them. The mechanism is widely assumed to require cleavage of GPN by cathepsin C, causing accumulation of amino acid residues, and osmotic lysis …