Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 6 of 6 for “"glutamate uncaging"”.
-
Spatiotemporal Dynamics of CaMKI During Structural Plasticity of Single Dendritic Spines
… hippocampal CA1 pyramidal neurons using 2-photon glutamate uncaging. Using RNA-interference and pharmacological means, we also characterize the role of CaMKI during spine structural plasticity. </p><p>We found that CaMKI was rapidly and transiently activated with a rise time of ~0.3 s and decay …
-
Layer specific differences in the mouse auditory corticocollicular system
… inputs. To do this, we utilized laser photo-uncaging of glutamate to stimulate the cells that synapse onto the layer 5 and layer 6 corticocollicular cells in brain slices taken from adult mice. Pre-identified cells were recorded in a whole cell patch configuration then stimulated with a …
-
RABPHILIN3A: FROM NMDA RECEPTOR MEMBRANE DYNAMICS TO NEURODEVELOPMENTAL DISORDERS
… It promotes the stabilization of the NMDA-type glutamate receptors (NMDARs) at the cell surface, forming a ternary complex with the PSD-95 and GluN2A subunit of the receptor. This complex is needed for long-term potentiation (LTP) induction and NMDAR-dependent hippocampal behaviors, such as …
-
Neocortical Layer 4 to Layer 2/3 Sensory Information Processing Investigated with Digital-Light-Projection Neuronal Photostimulation
… induce action potentials in 2.5 mM MNI-caged glutamate. At these settings the effective diameter of a glutamate uncaging site is < 86 µm, which is equivalent to most other UV photostimulation rigs. With DLP photostimulation, sub-threshold responses and action potentials can be synchronously …
-
A Three-Molecule Model of Structural Plasticity: the Role of the Rho family GTPases in Local Biochemical Computation in Dendrites
… and single-spine stimulation by two-photon glutamate uncaging, the activation profile and kinetics of Rac1 during synaptic stimulation were characterized. These experiments revealed that Rac1 conveys signals to both activated spines as well as nearby, unstimulated spines that are in close …
-
Dendritic properties of inhibitory thalamic neurons: implications in sub-cortical sensory processing
Item reinstated by Sarah Shreeves (sshreeve@illinois.edu) on 2014-06-28T10:00:20Z Item was in collections: Graduate Theses and Dissertations at Illinois (ID: 204) Neuroscience Program Dissertations (ID: 630) No. of bitstreams: 2 Crandall_Shane.pdf: 5543535 bytes, checksum: …