Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"glutamate metabolism"”.
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Key roles of glutamate metabolism and cuticle permeability in the multifaceted defense response of the abscisic acid deficient sitiens tomato mutant against Botrytis cinerea
… genes involved in central carbon/nitrogen (C/N) metabolism also significantly increased in the resistant mutant. In the present work, we have initially provided a review on the reconfiguration of plant central C/N metabolism in response to different pathogenic lifestyles, and the potential roles …
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Analysis of gene expression alterations in premalignant progression from normal mammary epithelium to ductal carcinoma in situ by multiple orthogonal tools
… expressed genes in DCIS is strongly linked to glutamate metabolism and others involved in dysregulation of various pathways such as IGF-1 signaling, integrin signaling and fatty acid biosynthesis. To further enrich the expression data and identify low abundance transcripts we employed next …
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Genomic Discovery of recurrent CD44-SLC1A2 Gene Fusion in Gastric Cancer
… genomic breakpoints in the SLC1A2/EAAT2 glutamate transporter. 5' RACE analysis of a breakpoint-positive cell line (SNU16) revealed expression of a CD44-SLC1A2 fusion transcript, caused by a paracentric chromosomal inversion, which was predicted to produce a truncated but functional …
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Surguvant inflammation and metabolism in colorectal surgery
… (POI) and altered cellular and systemic metabolism in the perioperative period may predispose to colon cancer recurrence. This thesis examined the ability to harness perioperative body composition, cell free DNA (cfDNA) and metabolomic data and apply these as prognostic markers and …
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Maximizing Local Access to Therapeutic Deliveries in Glioblastoma: Evaluating the utility and mechanisms of potential adverse events for minimally invasive diagnostic two novel therapeutic techniques for brain tumors
… explore possible bystander effects of H-FIRE on glutamate metabolism in the brain. H-FIRE has been shown to be able to both ablate brain tumors as well as disrupt the blood-brain barrier (BBB). As these therapeutic effects of H-FIRE are dependent on applying electrical fields to the tissue that …