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Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 175 for “"glucose uptake"”.
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Effects of naringenin on glucose uptake in L6 skeletal muscle cells
… insulin action and consequent high blood glucose levels. Type 2 diabetes accounts for the majority of cases of the disease and is characterized by insulin resistance and relative insulin deficiency resulting in metabolic deregulation. It is a complex disorder to treat as its pathogenesis …
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The Effect of Insulin on Glucose Uptake in Hypothalamic Appetite Centers
Made available in DSpace on 2014-12-10T17:37:48Z (GMT). No. of bitstreams: 1 6706763.pdf: 3735438 bytes, checksum: 43c09edc93e40df3f58350bb0fba5f08 (MD5) Previous issue date: 1966
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Regulation of Glucose Uptake and Transporter Expression in the North Pacific Spiny Dogfish (Squalus suckleyi)
… few carbohydrates and have little reliance on glucose as an oxidative fuel, the one exception being the rectal gland. This has led to a dearth of information on glucose transport and metabolism in these fish, as well as the presumption of glucose intolerance. Given their location on the …
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Investigating the Biological Effects of Rosemary (Rosmarinus officinalis L.) Extract on Skeletal Muscle Glucose Uptake
… is the most important tissue in maintaining glucose homeostasis and impairments in this tissue leads to insulin resistance (IR). Activation of 5’ AMP-activated kinase (AMPK) is viewed as a targeted approach to counteract IR. Rosemary extract (RE) has been reported to decrease blood glucose …
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Investigation of the Effects of Antipsychotics on CNS Insulin-mediated Brain Glucose Uptake using 2DG Autoradiography
… induce central insulin resistance and disrupt glucose regulation. Attenuated central insulin action has also been shown to be a critical factor in the development of age-related cognitive decline and Alzheimer’s disease (AD). As such, aberrant brain insulin signaling has been posited to lie at …
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TIME COURSE OF SIGNALING PROCESSES INVOLVED WITH EXTRACELLULAR OSMOTIC - INDUCED GLUCOSE UPTAKE IN MAMMALIAN SKELETAL MUSCLE
… hyper-osmotic (HYPER) stress increases glucose uptake to defend cell volume, when compared to iso-osmotic (ISO) conditions in skeletal muscle. The purpose of this study was to determine a time course for changes in common signaling proteins involved in glucose uptake during acute …
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Cassia cinnamon and acute endurance exercise for the enhancement of glucose uptake in healthy young women.
… placebo and endurance exercise on an oral glucose tolerance test (OGTT) blood glucose (BG), serum insulin (SI) values, fasting HOMA insulin resistance (HOMA-IR) and Matsuda insulin sensitivity (Mat-ISI). On three separate days, 10 women (22.7 ± 4 years, BMI of 35.39 ± 5.36) reported to the …
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Regulation of skeletal muscle glucose uptake during contraction/ exercise by nitric oxide (NO)/ neuronal nitric oxide synthase MU (NOSμ)
… muscle contraction, large amounts of blood glucose are taken up into skeletal muscle fibers thus removing glucose from the bloodstream. This process is regulated differently to insulin-stimulated muscle glucose uptake and is normal in humans with type 2 diabetes (T2D) and in diabetic rodent …
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Metaboloptics: In Vivo Optical Imaging to Enable Simultaneous Measurement of Glucose Uptake, Mitochondrial Membrane Potential, and Vascular Features in Cancer
… outcomes in cancer. In particular, increased glucose uptake independent of oxygenation is a well-known mark of aggressive cancers that are more likely to metastasize and evade certain therapies. Lately, mitochondria are also gaining recognition as key contributors in tumor metabolism, and …
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An in vitro study of the effects of free fatty acids on insulin mediated glucose uptake and metabolism by myocytes and fibroblast derived adipocytes
… tissues involved with post-prandial peripheral glucose disposal in response to insulin. Insulin resistance reduces the ability to clear glucose from the circulation resulting in hyperinsulinemia and hyperglycemia with the development of T2D. High levels of plasma free fatty acids (FFAs), …
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ELUCIDATION ON THE MECHANISM OF CAMKKα AS A PRO-GROWTH KINASE IN MOUSE SKELETAL MUSCLE
… been found to be beneficial on two levels. 1) Glucose uptake is increased in exercising skeletal muscle, which is crucial as skeletal muscle accounts for ~85% of insulin-stimulated glucose uptake and the insulin effect is blunted in type 2 diabetes. 2) Post resistance exercise, muscle protein …
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Biochemical Studies on Uncoupling Proteins and Glucose Metabolism in Skeletal Muscle
… uncoupling protein expression and alterations in glucose metabolism in different pathological conditions. In the first part of these studies, the expression of uncoupling proteins in pancreatic cancer patients was determined. A significant increase in UCP-3 and UCP-2 protein and mRNA expression …
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The effects of herbal extracts and compounds on the glucose metabolism in Hep G2 cells
… secondary metabolites and extracts on glucose metabolism in Hep G2 cellular models. The primary objective of this project is to evaluate and compare the metabolic activities of Hep G2 cells after treatment with pure compounds phloretin, ouabain, berberine, and metformin, rebaudioside-A, …
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Isolation of hog renal brush border membrane vesicles with application to the study of cadmium nephrotoxicity
… enzyme activity but appeared to have impaired glucose uptake activity. Since the Percoll-prepared vesicles seemed unsuitable for uptake studies, brush border membrane vesicles isolated by a differential precipitation method were used to investigate the effect of cadmium on glucose uptake. Of …
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Effects of Rosemary Extract and Rosemary Extract Polyphenols on Skeletal Muscle Insulin Resistance
… of insulin, accounts for ~80% of postprandial glucose disposal and plays a significant role in the regulation of glucose homeostasis. Insulin increases muscle glucose uptake by increasing the translocation of intracellularly stored GLUT4 glucose transporters to the plasma membrane through the …
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Metabolic Bioactivity of Athrixia phylicoides
… extract of Athrixia phylicoides to increase glucose uptake and utilization in myocytes, adipocytes and in Chang cells. It is therefore likely that this extract could also modulate glucose metabolism in insulin-resistant cells. This study investigated the effect of an aqueous A. phylicoides …
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Treating type 2 diabetes through insulin resistance
… muscle is the main site of insulin-stimulated glucose disposal and appears to be the first organ that becomes insulin resistant in the diabetic state, with later involvement of adipose tissue and the liver. This study has investigated the use of novel agents to ameliorate insulin-resistance in …
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Examination of Glucose Transport in Clostridium Beijerinckii NCIMB 8052 and the Solvent Hyper-Producing Mutant BA101
Glucose uptake and accumulation by Clostridium beijerinckii BA101, a butanol hyper-producing mutant was examined during various stages of growth. Glucose uptake in C. beijerinckii BA101 was repressed 20% by 2-deoxyglucose (2-DG) and 25% by mannose, while glucose uptake in C. beijerinckii 8052 was …
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