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Showing 1 to 8 of 8 for “"glucose transporter 1 (GLUT1)"”.
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HYPOXIA-REGULATED EXPRESSION OF GLUT-1 IN GBM CELL LINES
… 1 (HIF-1). HIF-1 is thought to directly affect glucose transporter 1 (GLUT1) expression levels in hypoxic conditions. This study sought to determine the relationship between HIF-1 and GLUT1 expression levels within normoxic and hypoxic environments utilizing an <em>in-vitro</em> GBM model. The …
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Different Effect of 5-Fluorouracil on Expression of Genes Related to Aerobic Glycolysis According to Chemoresponsiveness in Gastric Cancer Cells
… expressions of aerobic glycolysis related genes (GLUT1, PGK1 and PDK1), and the rate of glucose uptake in those cells. HIF 1α was highly expressed in SNU216, and the responsiveness of SNU216 to 5-FU was lower than it of MKN45. The expressions of glucose transporter 1(GLUT1), …
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Characterization of GSDMD as a Positive Regulator of Breast Cancer Cell Proliferation and Mammary Tumorigenesis
… protein-protein interaction between GSDMD and glucose transporter 1 (GLUT1), a protein pivotal in glucose uptake and metabolism. Here, we revealed that GSDMD and GLUT1’s interaction synergistically enhanced glucose transport activity and cell proliferation in BC cells. Future elucidation of …
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Regulation of glucose transporters in sheep placenta
Transplacental glucose transport is vital to fetal growth. Although the presence of glucose transporter-1 (GLUT1) and GLUT3 has been demonstrated in mammalian placenta, the factors regulating these genes remain unclear. Therefore, the overall aim of these studies was to clone ovine GLUT1 (oGLUT1) …
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Mechanism of mitochondrial respiratory dysfunction by oncogenic K-Ras
… mainly through glycolysis without induction of glucose transporter 1 (GLUT1), which has a low Km value and is a well-known glucose transporter induced by oncogenic Ras signaling. Finally, LC3-II formation, which is indicative of autophagy initiation, was modulated by extracellular glucose levels …
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Suppression of Carcinogenesis and Tumor Progression by an Energy Restriction-Mimetic Agent in Murine Models of Prostate Cancer
… that can induce a response similar to that of glucose restriction in vitro and caloric restriction in vivo are needed. These agents are termed energy-restriction mimetic agents (ERMAs) and include 2-deoxyglucose, resveratrol, and the thiazolidinedione derivatives OSU-CG12 and OSU-CG5. Here, we …
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Small molecule kaempferol, a novel regulator of glucose homeostasis in diabetes
… 5 months (mo) improved insulin sensitivity and glucose tolerances, which were associated with increased Glut4 and AMPKα expression in muscle and adipose tissues in middle-aged mice fed a high-fat (HF) diet. In vitro, kaempferol increased lipolysis and restored chronic high fatty acid-impaired …
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Small molecule inhibitors of lactate dehydrogenase A as an anticancer strategy
Embargo set by: Seth Robbins for item 73141 Lift date: 2017-01-21T19:56:18Z Reason: Author requested U of Illinois access only (OA after 2yrs) in Vireo ETD system