Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 50 for “"glucose transport"”.
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The Importance of Glucose Transport in Reproductive Events
ABSTRACT OF THE DISSERTATION The Importance of Glucose Transport in Reproductive Events by Katie Lynn Adastra Doctor of Philosophy in Biology and Biomedical Sciences Developmental, Regenerative and Stem Cell Biology Washington University in St. Louis, 2012 Professor Kelle H. Moley, Chairperson …
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Examination of Glucose Transport in Clostridium Beijerinckii NCIMB 8052 and the Solvent Hyper-Producing Mutant BA101
Glucose uptake and accumulation by Clostridium beijerinckii BA101, a butanol hyper-producing mutant was examined during various stages of growth. Glucose uptake in C. beijerinckii BA101 was repressed 20% by 2-deoxyglucose (2-DG) and 25% by mannose, while glucose uptake in C. beijerinckii 8052 was …
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Sodium and glucose transport across the in vitro perfused midgut of the blue crab, Callinectes sapidus Rathbun
… the present study are: (1) to investigate sodium transport across the midgut as well as the hindgut of Callinectes sapidus and the functioning of these two regions of the gut in osmotic and ionic regulation of the animal, and (2) to elucidate the mechanism of glucose absorption across the midgut …
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The Role of Leucine and Its Metabolite (KIC) in Insulin Signalling and Glucose Transport in L6 Myotubes
… the presence or absence of other amino acids on glucose transport in L6 rat myotubes. Here we report that leucine significantly suppresses insulin-stimulated glucose uptake in skeletal muscle cells and particularly at 150 M, there is a 75% reduction in insulin-mediated glucose transport (p<0.01). …
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The role of PLC, cPKC, L-type calcium channels and CAMKII in insulin stimulated glucose transport in skeletal muscle
There is no abstract available for this dissertation.
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Methionine and glucose transport by isolated intestinal brush border membrane vesicles from pigs and lambs fed an Aspergillus product
… as indicated by uptake of methionine and glucose by isolated intestinal brush border membrane vesicles (BBMV). In Experiment 1, 24 weanling pigs were paired by sex, BW, and litter and were allotted, within pairs, to either an 18% CP corn-soy diet (control) or the same diet supplemented …
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Butyrate-induced upregulation of intestinal glucose transport and signaling pathways represent a possible nutrient therapy for individuals with malabsorptive disorders
… Interventions aimed at increasing intestinal transport capacity may mitigate the negative consequences of a damaged intestine, and reduce the need or intensity of costly supportive therapies. Attaining nutrients is a careful orchestration of diet, digestion, and absorption. In a typical …
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Effects of Zinc on the Insulin Receptor and Insulin Signal Transduction Pathway
… affinity. The study about the stimulation of glucose transport by zinc revealed that zinc affected the insulin intracellular signaling pathway. Zinc enhanced glucose transport in the presence and absence of insulin in 3T3-L1-preadipocytes and -adipocytes. The effect of zinc plus insulin was …
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Investigation of potential intervention targets to improve insulin action: a therapeutic approach
… increase in protein synthesis with facilitated glucose transport, and was independent of the serotonin and noradrenaline reuptake inhibition produced by sibutramine. Pinitol (a methyl inositol) had an insulin mimetic effect and was an effective glucose-lowering agent in insulinopenic states, …
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Characterisation of the role of AMP-activated protein kinase in 3T3-L1 adipocytes
… syndrome. In skeletal muscle AMPK stimulates glucose uptake and fatty acid oxidation, whereas in liver it inhibits fatty acid and cholesterol synthesis. The Rab GTPase activating proteins Akt substrate of 160 kDa (AS160) and tre-2/USP6, BUB2, cdc16 domain family member 1 (TBC1C1) have been …
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Influence of dietary polyphenols on carbohydrate intestinal digestion and absorption
… and beverages may modify glycemic response, glucose homeostasis and subsequent risk of Type-2 diabetes. <em>In vitro</em> evidence typically derived from experiments with pure phenolics and phenolic rich extracts have pointed to this benefit being associated with two potential mechanisms: (1) …
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Hexose Transport In L6 Rat Myoblasts
… the nature and the regulation of the hexose transport system in the permanent cell line, L6. This rat myoblast line can differentiate in culture to form multinucleated myotubes, but in this study, only the undifferentiated cells were used. Kinetic and inhibition studies suggested that the …
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Effects of Chronic High Sucrose With Dietary or Drinking Inclusion on the Electrogenic Glucose Absorption in the Intestinal Tract of Mice (Mus musculus)
… on the intestinal electrogenic sodium dependent glucose transport, the first portal of entry for glucose, is unknown. Here female C57bl/6 mice fed a normal standard chow diet, and 20% sucrose in the drinking water for 8 months, or 35% sucrose inclusion in the diet for 12 months were assessed. The …
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Effect of non-esterified fatty acids on insulin resistance and cardiovascular risk in polycystic ovary syndrome
… muscle of PCOS and it affects insulin mediated glucose transport in the presence of lipid in vitro studies.Methods: The effect of non-esterified fatty acids (NEFA) on IR, postprandial lipids and cardiovascular risk in obese women with PCOS compared to controls was examined by lowering NEFA …
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Short-Chain Fatty Acids and Functional Adaptations in the Neonatal Intestine
… that butyrate (Bu) results in marked changes in glucose transport in the intestine within minutes. We hypothesized that SCFA and Bu would enhance glucose transport and transporter gene expression in a neonatal pig model of massive small bowel resection. Two-day-old neonatal pigs underwent 80% …
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THE EFFECTS OF OBESITY ON PLASMA LEVELS OF OMENTIN, A DEPOT-SPECIFIC ADIPOCYTOKINE
… adipose tissue that increases insulin-stimulated glucose transport. To further elucidate omentin's physiological function, its levels were measured by quantitative western blotting in plasma from 44 healthy nondiabetic volunteers (22 women, 22 men). Participants were organized into sibling pairs …
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Sweet relief: regulating the response to glucose phosphate stress by the small RNA SgrS & Co.
Cells use complex mechanisms to regulate glucose transport and metabolism to achieve optimal energy and biomass production while avoiding accumulation of toxic metabolites. Glucose transport and glycolytic metabolism carries the risk of the buildup of phosphosugars, which can inhibit growth at high …
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The regulation of ceramide content and insulin resistance in skeletal muscle
… stimulus (100 ,aU/ml) increased 3-O-methylglucose transport by -2.7 fold over basal conditions in the soleus (1.90 ± 0.23 µmol•ml"1•hr-1 vs. 5.06 ± 0.38 µmol•ml-1•hr-1, respectively) (P < 0.05). Five hours of palmitic acid preincubation induced a significant decrease in insulin-stimulated …
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A Study of the Effects of Various Levels of Cranially Applied Electricity on Passage of Glucose from Cerebral Circulation into the Brain
… EA, but little is known about the effects on glucose transport into the brain. Procedure. Thirty male rats were subdivided into 6 groups of 5 each, 1 serving as the control and the remaining 5 as experimental. The right common carotid artery was surgically exposed in all rats and a solution of …
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Characterization of GSDMD as a Positive Regulator of Breast Cancer Cell Proliferation and Mammary Tumorigenesis
… protein-protein interaction between GSDMD and glucose transporter 1 (GLUT1), a protein pivotal in glucose uptake and metabolism. Here, we revealed that GSDMD and GLUT1’s interaction synergistically enhanced glucose transport activity and cell proliferation in BC cells. Future elucidation of …
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