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Showing 1 to 20 of 32 for “"glucose regulation"”.
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Mathematical modelling of blood glucose regulation
… to model the effects of exercise on the glucose regulatory system, for both healthy and diabetic individuals. A particular focus is given to the role of glucagon, whose role is often neglected in glucoregulatory models, and its ability to enhance hepatic glucose production and so to …
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Chronic Circadian Disruption Alters Behaviour, Cardiac Function and Glucose Regulation in Mice
… electrocardiograms in the first 4 months, and a glucose or insulin tolerance test and several behavioural assays at 13 weeks. We found that mice raised in mismatched LD cycles had worse health outcomes, including heightened blood glucose after glucose or insulin bolus, altered cardiac …
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The Acute Effect of Water Intake on Glucose Regulation in Low Drinkers
… the acute effect of adequate water intake on glucose regulation in low drinkers. Methods: 7 healthy (5 males, 2 female) low drinkers were recruited using a water frequency questionnaire (WFQ), spot and 24-h urine sample (age 43±6 y, BMI 30.9±3, WFQ volume 823±403 mL∙d-1, 24 h Uosm 961±105 …
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The Effect of Cellular Dehydration on Glucose Regulation in Lean and Obese Females
… level has been associated with an impaired glucose regulation system in humans. A recent study in patients with diabetes suggested that low water intake is associated with impaired glucose regulation. The aim of this study was to examine the effect of hypertonic saline infusion on glucose …
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Novel nutritional interventions in the manipulation of energy expenditure and blood glucose regulation in humans
… on components of energy balance and blood glucose regulation. Studies of their supplementation among humans are none (in case of L-Histidine) or very limited (in case of EGCG supplementation). The studies presented herein are novel as there have been no previous studies conducted to measure …
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The effect of glucose regulation on cognitive functioning in a healthy sample of older adults
Type II diabetes and impaired glucose tolerance (IGT) are both associated with cognitive impairment and an increased risk of dementia, and normal aging has been shown to be accompanied by abnormalities in glucose regulation. The present study was conducted to determine if variations in cognitive …
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Glucose regulation in Thoroughbred weanlings: Regulation by insulin, growth hormone and insulin-like growth factor-I
… horses. This study applied the minimal model of glucose and insulin dynamics to determine the effect of diet on metabolites and hormones that regulate glucose metabolism in young horses. Twelve Thoroughbred foals were raised on pasture and supplemented twice daily with a feed high in either sugar …
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Models and nonlinear control strategies for blood glucose regulation in artificial pancreas [Modelli e strategie di controllo non lineare per la regolazione della glicemia nel pancreas artificiale]
Il diabete di tipo 1 è una malattia autoimmune in cui il sistema immunitario attacca e distrugge accidentalmente le cellule beta nel pancreas, limitando la capacità dell'organo di produrre insulina. Un pancreas artificiale è una tecnica che utilizza una pompa per somministrare la giusta …
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The upper small intestinal microbiota regulates nutrient sensing pathways to influence glucose homeostasis
… Type 2 Diabetes, which is characterized by a dysregulation in glucose homeostasis. The microbiota within the gastrointestinal tract has been suggested to play a role in glucose regulation. However, the majority of work to date has focused on the distal intestinal microbiota despite the fact that …
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Chickens from lines artificially selected for juvenile low and high body weight differ in glucose homeostasis and pancreas physiology
… hyperglycemic, displaying fasting blood glucose concentrations twice that of a normal human. While circulating levels of insulin are similar in avians and mammals, and structure and function of the insulin receptor are also conserved among vertebrate species, birds do not experience …
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Glucose disposal and insulin sensitivity at rest and during exercise in trained horses adapted to different dietary energy sources and in association with laminitis in ponies
Glucose is a fundamental energy source, the utilization and regulation of which impacts exercise performance and health. These studies have used modeling techniques to evaluate glucose kinetics and dynamics in equids and developed tests to evaluate the status of glucose metabolism. In Part I, 12 …
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Linear Modeling and Prediction in Diabetes Physiology
… the organism to autonomously regulate the blood glucose level due to insulin deficiency or resistance, leading to serious health damages. The therapy is essentially based on insulin injections and depends strongly on patient daily decisions, being mainly based upon empirical experience and rules …
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Modeling and Prediction in Diabetes Physiology
… the organism to autonomously regulate the blood glucose levels. It requires continuing medical care to prevent acute complications and to reduce the risk of long-term complications. Inadequate glucose control is associated with damage, dysfunction and failure of various organs. The management of …
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Impact of mtDNA Signature on Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) Progression and Cardiometabolic Outcomes in Mice
… Morphometric, biochemical, histological, and glucose homeostasis assessments revealed that mtDNA background influenced hepatic lipid deposition and glucose regulation. These findings indicate that mtDNA variation modulates disease onset and trajectory under dietary stress in mice. …
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Investigation of the Effects of Antipsychotics on CNS Insulin-mediated Brain Glucose Uptake using 2DG Autoradiography
… induce central insulin resistance and disrupt glucose regulation. Attenuated central insulin action has also been shown to be a critical factor in the development of age-related cognitive decline and Alzheimer’s disease (AD). As such, aberrant brain insulin signaling has been posited to lie at …
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A RANDOMIZED STUDY OF THE GLUNOVO REAL-TIME CGM EFFECTIVENESS ON METABOLIC CONTROL IN PATIENTS WITH T2D
… the effectiveness of the real-time continuous glucose monitoring (RT-CGM) system, Glunovo, in improving glycemic control and patient outcomes in individuals with poorly controlled type 2 diabetes (T2D) compared to traditional self-monitoring of blood glucose (SMBG). Research Design and Methods: …
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Examining the placenta’s role in neurodevelopment in the context of maternal obesity
… several cell types, MO was associated with upregulation of hypoxia response genes. On only the maternal-facing side, hypoxia gene expression was associated with offspring neurodevelopment outcomes measured at multiple time-points, in the Genetics of Glucose regulation in Gestation and Growth …
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Evaluation of sweet taste perception in habitual and non-habitual consumers of low-calorie sweeteners
… findings suggest that LCS may be impacting glucose regulation and could cause decreased insulin sensitivity in some consumers. Though exact mechanisms of these effects are unclear, it is possible that these changes in glucose regulation may be mediated by LCS-related changes in the signaling …
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The interaction between glucose and fat metabolism and insulin resistance in severely burned children and the metabolic effects of fenofibrate
… in conjunction with disturbances in fat and glucose metabolism and mitochondrial dysfunction. Four human studies were conducted to better understand this relationship in the settings of aging and burn trauma. \r\nThe first two studies focused on aging. Insulin resistance commonly occurs in …
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