Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 5 of 5 for “"glucosamine-6-phosphate"”.
-
Regulation of glucosamine-6-phosphate synthase synthesis by a hierarchical acting cascade composed of two small regulatory RNAs in <i>Escherichia coli</i>.
Aminozucker sind essentiell für die Biosynthese der bakteriellen Zellwand und der Lipopolysaccharide. Das Enzym Glukosamin-6-Phosphat Synthase katalysiert die Bildung von Glukosamin-6-Phosphat (GlcN6P) aus Fruktose-6-Phosphat und Glutamin. Dies ist der erste Schritt der Aminozuckerbiosynthese. In …
-
Computational studies of the self-cleavage mechanism in the glmS ribozyme
… The glmS ribozyme regulates the level of glucosamine-6-phosphate (GlcN6P) in bacteria by catalyzing a self-cleavage reaction. Namely, the GlcN6P bonds to the glmS ribozyme and triggers a cleavage of a phosphodiester bond at a certain position via a general acid-base mechanism. This work …
-
Regulatory RNAs at the Heart of Sugar Metabolism: New Mechanisms and Novel Discoveries
… pathways in B. subtilis. The glmS RNA is a glucosamine-6-phosphate responsive element that regulates the expression of the GlmS enzyme, which directs sugar precursors from glycolysis into the cell wall biosynthesis pathway. The EAR element resides within the 16-kb eps operon that is required …
-
"Sugar Coat" Genetic & chemical validation of <i>Aspergillus fumigatus</i> cell wall targets
… a linear polymer of β-(1,4) linked N-acetylglucosamine (GlcNAc), forms a rigid inner layer that is also partially hydrolysed during morphogenesis by glycoside hydrolase family 18 plant-type chitinases. In contrast, exploitation of glucosamine-6-phosphate N-acetyltransferase (GNA1) an enzyme …
-
Cell wall metabolite levels as a function of the growth phase in Staphylococcus aureus and library screening for synergistic combinations of FDA approved drugs against methicillin resistant S. aureus
… their utilization. Retention and separation of glucosamine-1-phosphate (GlcN-1-P) and glucosamine-6-phosphate (GlcN-6-P) on a reverse-phase column is not feasible due to their high polarity. The second part of this study tested and demonstrated several derivatization procedures to improve the …