Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 197 for “"glial cells"”.
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Estrogen's Effects on Oxidative Stress Levels in Glial Cells
… We measured the oxidative stress level ofN1 1321 glial cells that were exposed to 600pM hydrogen peroxide. The astrocytes were pretreated for one hour with one of four types of estrogen at four concentrations ranging from 10nM - 10 uM. Two endogenous human estrogens, 17 alpha-estradiol and 17 …
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The effect of heavy metals on differentiated neuronal and glial cells
… of numerous heavy metals on neuronal and glial cell differentiation. Using established cellular models, the toxicity of zinc, lead, mercury, methylmercury and thimerosal were investigated using assays of cell viability and morphology on differentiating N2a and C6 cells. Initial research …
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Higher order chromatin degradation induced by hydrogen peroxide in glial cells
… study in nuclei purified from C6 glioma cells revealed that the endonuclease responsible for digestion is calcium-independent, but magnesium-dependent. Magnesium-induced HOCD was not affected by the removal of calcium from nuclei with ethylene glycol-bis(beta-aminoethyl ether)-N,N,N …
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Investigation of the role of polyploidization in glial cells during the development of the drosophila nervous system
… properly. Polyploidization is a process by which cells increase their DNA content and is used across species to generate large cells. Our lab had previously determined that subperineurial glia (SPG) of the Drosophila melanogaster nervous system become polyploid by both the endocycle and …
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The circadian role of Pex5 in glial cells and implications of Pex5 in sleep behavior and brain lipidome
Peroxisomes are critical organelles that detoxify cellular waste while also catabolizing and anabolizing lipids. How peroxisomes coordinate protein import and support metabolic functions across complex tissues and timescales remains poorly understood in vivo. Using the Drosophila brain, we discover …
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Aquaporin 4 and Kir4.1 Distribution in Retinal Glial Cells of Normal Macaque Eyes and Eyes with Experimental Glaucoma
… to glutamine synthetase (GS, a marker for Müller cells), and a polyclonal antibody to glial fibrillary acidic protein (GFAP, a marker for astrocytes and reactive Müller cells). Antibody binding in retina was visualized with the appropriate secondary antibody conjugate of fluorescein, Cy3 and Cy5. …
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A Study on the Effect of Peroxisome Proliferator-Activated Receptors (PPARs) Activation in Cultured Rat Brain Glial Cells
… inflammation in cultured rat brain glial cell. In LPS-stimulated rat glial cells, we observed activators of PPAR-? inhibited pro-inflammatory mediators, including tumor necrosis factor-alpha (TNF-?), interleukin-6 (IL-6), interleukin-1 beta (IL-1?) and monocyte chemoattractant …
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Glial activation in a mouse model of endometriosis and impact of Di(2-ethylhexyl) phthalate on glial cells, ileum, and colon
Submission published under a 24 month embargo labeled 'Closed Access', the embargo will last until 2024-12-01
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The role of potassium buffering and apoptosis of trigeminal satellite glial cells in the induction and maintenance of orofacial neuropathic pain in rats
Satellite glial cells (SGC) are laminar cells that wrap completely around the sensory neuron and are responsible for buffering extracellular K+ after neuronal excitation. A decrease in the potassium buffering capacity of SGC has been associated with neuropathic pain (NP) behavior and apoptosis. …
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Characterization of subtypes of precursor cells in the developing central nervous system
The role of radial glial cells as guides for migrating neurons is well established, whereas their role as precursor cells is less understood. Here we examined the composition of radial glial cells and their proliferation in the mouse telencephalon during development. We found that almost all radial …
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Differential Expression of Cell Adhesion Molecules by Neuronal Injury
Cell adhesion molecules(CAMs) are expressed in glial cells and neurons play critical roles in development and maintenance of nervous system. CAMs are reported that may be key molecular determinants in the response of the nervous system to injury. Therefore we are thought to that the expression of …
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Characterization Of Adult Zebrafish Retinal Regeneration Following Two Different Damage Models
… all of their retinal neurons through Müller glial cells, which respond to retinal damage by re-entering the cell cycle to create clusters of progenitor cells. The progenitors continue to proliferate as they migrate to the site of damage, where they ultimately differentiate into new retinal …
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Regulation of Neuropeptide Y, Vasoactive Intestinal Polypeptide, and Their Receptors in Trigeminal Ganglion Neurons and Glia in Response to Adjuvant-Induced Inflammation
… in Day 1 and Day 5 tissues, with localization to glial cells, and to both neurons and glial cells, respectively. NPY receptor, NPY Y₂ was upregulated in Day 1 tissues, localized to neurons and glia. VIP expression was observed in Day 1 and Day 5 tissues, with localization to glial cells, and to …
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The Involvement of Progesterone in Glial Cell Viability
… on the viability of hydrogen peroxide stressed glial cells. We wanted to determine the extent in which varying concentration of ethynodiol diacetate affect cell viability of cultured glial cells from hydrogen peroxide toxicity. Based on previous studies, we predicted that the viability of …
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Identification and characterization of glial and neuronal cells in vitro and in bone marrow
This study attempts to identify and characterize glial cells and neuronal cells in avian brain and mammalian bone marrow, respectively. The project has four major objectives: (a) to culture and maintain avian glial and neuronal cells up to 20 days, (b) to examine cell cultures using selective …
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