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Showing 1 to 2 of 2 for “"gilteritinib"”.
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An Investigation into the Potential of Cell Therapies for Acute Myeloid Leukemia (AML) Treatment
… with approved AML therapies cytarabine, gilteritinib, and venetoclax, the apoptotic effect induced by iPSC-NKs increased in an E:T and dose-dependent manner, with iPSC-NK viability unaffected by cytarabine. Similarly, we observed donor-derived Vγ9Vδ2 T cells induced E:T-dependent …
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Concomitant Inhibition of Flt3 and Mcl-1 In Flt3 Mutated Acute Myeloid Leukemia
<p>The MCL-1 inhibitor S63845 synergizes with the FLT3 inhibitor midostaurin for potent anti-leukemic effect in preclinical human models of FLT3-ITD mutated acute myeloid leukemia (AML). Acute Myeloid leukemia (AML) is a neoplastic blood disorder defined by a characteristically rapid growth rate …