Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 2 of 2 for “"germline mutants"”.
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CATALYTIC-INDEPENDENT FUNCTIONS OF KDM6A IN B CELL MATURATION AND IMMUNE REGULATION
… analysis was conducted on B cells from germline mutants expressing a catalytically inactive Kdm6a protein. Notably, defects observed in B-cell-specific Kdm6a null mice, including impaired follicular/marginal zone B-cell differentiation, reduced GC B-cell pool size, contraction of the PP …
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CRISPR/CASTE: Functional Genomic Studies of the Major Evolutionary Innovations of Ants
… focus on generating and characterizing germ-line mutants. I believe that the study of mutants, and applying molecular biology methods more generally, can lead to insights in ant biology that would not be possible with more traditional methods. I first describe my efforts to develop a CRISPR …