Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"geographic atrophy"”.
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Optical Coherence Tomography Angiography for Imaging and Analysis of the Choriocapillaris in Late Age-Related Macular Degeneration
… impairment in macular neovascularization and geographic atrophy, the two subtypes comprising late AMD. The choriocapillaris, the capillary layer of the choroid, is responsible for nourishing the outer retina, including the photoreceptors, and has long been hypothesized to have an important …
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Development of preformed photo-crosslinked intravitreal implants for protein delivery to the posterior segment of the eye
… (AMD), diabetic retinopathy (DR), and geographic atrophy, all of which can cause vision impairment and often, blindness. Controlled delivery systems can minimise the frequency of injections by extending the residence period of active medications at the site of administration. Possible …
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Regulating the bioactivity of placental growth factor in the aging outer retina as a new therapeutic approach to age-related macular degeneration
… disease presents as neovascular AMD (NV-AMD) or geographic atrophy (GA). Advances in angiogenesis research have led to the development of treatments for patients with NV-AMD. However, there are no clinically available treatments for GA. Placental growth factor (PlGF) is a seemingly dispensable …
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Graph Theory and Dynamic Programming Framework for Automated Segmentation of Ophthalmic Imaging Biomarkers
… and was capable of segmenting both drusen and geographic atrophy. To account for the complex manifestations of DME, a novel kernel regression-based classification framework was developed to identify retinal layers and fluid-filled regions as a guide for GTDP segmentation.</p><p>The development …
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Vascular breakdown in diabetic retinopathy: Role of connexin43 and possible interventions
… treatments have been shown to contribute to geographic atrophy and retinal ganglion cell death. Therefore, alternative treatments that target upstream disease mechanisms are needed. Recent studies have shown that connexin43 hemichannels play a role in the pathogenesis of chronic inflammatory …