Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 2 of 2 for “"genome-wide CRISPRi"”.
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Uncovering the biogenesis pathways for human mitochondrial alpha-helical outer membrane proteins using genome-wide approaches
… proteins which are encoded in the nuclear genome, synthesized in the cytosol and must be targeted to the membrane. OMM proteins are defined by the secondary structure of their transmembrane domains (TMDs), as two classes – beta-barrel proteins, evolutionarily derived from the outer …
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Investigating the Double-Edged Sword of Rifampicin Resistance in Mycobacterium Tuberculosis
… to 450,000 cases of TB and 264,000 deaths worldwide in 2021. Treatment for drug resistant TB is even more arduous, consisting of expensive second- and third-line antituberculars with side effects such as deafness, hepatotoxicity, and peripheral neuropathy, taken for six to nine months. RifR is …