Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 8 of 8 for “"genetic redundancy"”.
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SIMPLIFIED TRAIT AND GENE DISCOVERY FOR DROUGHT RESILIENCE IN WHEAT USING EINKORN WHEAT
… and abiotic stresses, particularly drought. Genetic improvement remains the most sustainable strategy for enhancing stress resilience and yield stability; however, gene discovery in bread wheat is complicated by its allohexaploid genome (AABBDD, 2n = 6x = 42) and extensive genetic redundancy. …
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Dissecting the NCR Peptide Landscape in the R108 Ecotype in Medicago Truncatula and the Search for the NF21325 Symbiotic Mutant
… suggest a partial loss-of-function or complex genetic redundancy. To address R108’s limited genomic characterization, a bioinformatics pipeline identified novel NCR homologs and expanded the canonical NCR definition by uncovering non-cysteine peptides. Using homology-based clustering, R108 NCRs …
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Meristem regulation in the early divergent land plant Marchantia polymorpha
… targeted to engineer crop development. However, genetic redundancy and morphological complexity present powerful obstacles to explore engineering of meristem regulation. Marchantia polymorpha is an early divergent land plant which has received re-surging interest as a model plant, following the …
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Genetic algorithms with implicit memory
This thesis investigates the workings of genetic algorithms in dynamic optimisation problems where fitness landscapes materialise that are identical to, or resemble in some way, landscapes previously encountered. The objective is to appraise the performances of the various approaches offered by the …
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Control of Cardiac and Limb Development by the bHLH Transcription Factors DHAND and eHAND
… during cardiac valve formation, and demonstrated genetic redundancy of HAND genes during mammalian cardiac morhpogenesis. Finally, we have utilized tissue culture assays and transgenic mice to investigate the mechanisms by which dHAND regulates transcription of downstream target genes. These …
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Determining how variations in cell and nuclear size contribute to mitosis and tumorigenicity in cancer cells that undergo whole genome doubling
… with metastasis and poor prognosis. The genetic redundancy afforded by WGD is thought to attenuate the deleterious effects of gene mutations and chromosome missegregation, thereby enabling the propagation of genomic and functional diversity that promote cancer evolution. This is supported …
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Characterisation and functional analysis of a novel msp domain – containing protein, MOSPD1
… thesis were to investigate the possibility of genetic redundancy between Mospd 1 and Mospd 3 by identifying the sub-cellular localisation of MOSPD1 and MOSPD3 in both cells and tissues and to investigate the function of MOSPD1. Mouse monoclonal antibodies specific for MOSPD1 and MOSPD3 were …
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A Combined Computational Strategy of Sequence and Structural Analysis Predicts the Existence of a Functional Eicosanoid Pathway in <i>Drosophila melanogaster</i>
… challenges this currently held view. Molecular-genetic and biochemical analyses of individual biosynthetic enzymes in <em>D. melanogaster</em>, a model organism with low genetic redundancy will reveal if the fly enzymes are functionally equivalent to their mammalian counterparts; their <em>in …