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Showing 1 to 1 of 1 for “"genetic modification of Trypanosoma brucei"”.
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Molecular mechanism of Trypanosoma brucei Aquaglyceroporin 2
Trypanosoma brucei subspecies cause Human African Trypanosomiasis, which is fatal unless treated. T. brucei Aquaglyceroporin 2 (TbAQP2) is required for the uptake of two of the drugs used clinically, pentamidine and melarsoprol. TbAQP2 mutations or the formation of a chimeric gene with TbAQP3 …