Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 38 for “"genetic map"”.
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Genetic map of coliphage 186
xxi, 278 leaves : photos, tables, graphs ; 30 cm.
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A Chemical-Genetic Map of Drug Resistance in Mycobacterium Tuberculosis
… diagnostics. We sought to understand the genetic basis drug resistance in Mtb using a novel CRISPR interference (CRISPRi)-based chemical genetics platform. Our lab developed a CRISPRi library containing 100,000 unique knockdown strains and treated this library with a panel of some of the …
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Distortions of the genetic map of chromosome I in Caenorhabditis elegans
The process of meiosis ensures heritable genetic material is passed faithfully from one generation to the next. To identify the mechanisms involved in this process, the effects of sex, mutation, and rearrangement on meiotic recombination in Caenorhabditis elegans were investigated. The short life …
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A complete genetic map of the mouse and its application to the study of mouse models of human disease
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Biology, 1993.
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Molecular Genetics on the Genus Glycine: I. Phylogenetic Study of the Subtribe Glycininae. II. Development of a Universal Soybean Genetic Map
During the last decade various soybean genetic linkage maps have been developed based not only on morphological and biochemical traits but also on molecular traits such as RFLP, RAPD, AFLP, and SSR data. None of these, however, has been associated with specific chromosomes of soybean. Therefore, …
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Linkage mapping and genetic analysis of Trypanosoma brucei
… of T.brucei is now available and the diploid genetic system has recently been demonstrated to be Mendelian. This opens up the possibility of using a classical genetic approach to identify genetic loci that determine important phenotypic traits in this parasite, such as host specificity, drug …
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Linkage fine-mapping, GWAS and QTLs affecting morpho-agronomic traits of a common bean RIL population
… food security on the world. In this sense, genetic breeding is essential to obtain more productive cultivars, with plant architecture more adequate to the harvesting systems, with a cycle suitable to the regions of production, and grain type compatible with the requirements of the local …
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Structure, Regulation and Comparative Biochemistry of the Pyrimidine Biosynthetic Gene Cluster in Bacillus Subtilis (Atcase)
… coli pyrB, C, D, E, and F mutants. A restriction map of the cluster was generated, and many subclones were analyzed for their ability to complement E. coli pyr mutants. From these data a genetic map was generated; the gene order is pyrBCADFE. The B. subtilis pyrB gene was shown to be expressed in …
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SSR-based genetic mapping of QTLs determining chilling requirements for time of initial vegetative budbreak in domesticated apple (Malus x domestica Borkh.) cultivar ‘Anna’ x ‘Austin’
… and Diversity Array Technology (DArT) genetic markers have been exploited in this work and are essential tools in genetic map construction and marker-assisted selection (MAS) of high quality apples and other rosaceous crops. Microsatellites are advantageous in that they are co-dominant, …
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The development of tools to allow genetic and genomic analysis of Frankia
… dicotyledonous plants. The lack of standard genetic tools for this important bacterium has hindered studies on the molecular biology of this symbiosis. We are interested in developing tools for the genetic analysis of Frankia physiology and its interactions with its host plants. Our approach …
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The Evolution of Recombination Landscapes and Mechanisms in Drosophila in Light of Intragenomic Conflict
… for manipulation and exploitation by selfish genetic elements. Selfish elements can increase in abundance independently of their host organism and frequently at a cost to host fitness. Several types of selfish elements act during meiosis and therefore it is possible for recombination rates and …
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Analyses of a genic male-sterile mutant in soybean
… male-sterile mutant in soybean was characterized genetically, developmentally, and molecularly. This mutant is controlled by a single recessive gene, which is not allelic to six previously identified soybean genic male-sterile mutants: ms1, ms2, ms3, ms4, ms5, or ms6. No linkage was detected …
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Identification of genetic markers associated with growth and morphology quality in senegalese sole (solea senegalensis) to boost aquaculture production
… to solve these problems but requires estimate genetic components of economically valuable traits such as those growth and morphology related under industrial conditions. By other side, the advances in genomics provide new highly powerful analysis tools to determine more accurately genetic …
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Systems View Of The Soybean Genetic Mechanisms Involved In The Response To Plant Pathogen Infection
… a rich information resource for breeders and geneticists working towards improving traits for pathogen resistance.Results reported here provide a systemic view at both the genetic and biochemical level, and were generated by data-mining gene expression data from soybean cultivars inoculated …
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Cytogenetics and genome structure in genus Miscanthus, a potential source of bioenergy feedstocks
… of self-incompatibility, a complete genetic map with a high density of markers has not yet been developed. As described in chapter 3, a cross between two M. sinensis accessions, ‘Grosse fontaine’ and ‘Undine’ was made to produce 221 segrating progeny as a mapping population. Simple …
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Candidate Gene Expression and SNP Analyses of Toxin-Induced Dilated Cardiomyopathy in the Turkey(Meleagris gallopavo)
… often occurs without a consensus cause. Though genetic and other studies of IDCM are extensive, the specific etiology of toxin-induced is still unknown. Here, our objective was to compare the level of mRNA expression of two candidate genes including troponin T (cTnT) and phospholamban (PLN) …
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Isolation and characterization of a synthetic gene and a genomic clone encoding acyl carrier protein from Escherichia coli
… The ACP gene (called acpP) was located on the genetic map between fabF and fabD which encode two fatty acid biosynthetic enzymes, 3-ketoacyl-ACP synthase II and malonyl CoA-ACP transacylase, respectively. An open reading frame between acpP and fabD encodes a 26.5-kDa protein that has …
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Use of a conservation-of-linkage strategy to identify a candidate for the rat Lymphopenia gene
… large-scale YAC and fine-scale P1/BAC physical maps of the mouse Lyp region, and integrated these maps with a fine-scale genetic map of the rat Lyp region. Using cDNA fragments obtained through direct cDNA selection, we established a transcript map of the mouse Lyp region. One of these …
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Identification, Validation, and Mapping of Phytophthora sojae and Soybean Mosaic Virus Resistance Genes in Soybean
… Disease phenotyping has generated a preliminary genetic map for resistance in soybean accession PI408132. The identification of novel R-genes will allow for stacking of resistance loci into elite G. max cultivars. The second project covered in this dissertation describes the validation of the SMV …
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Tales of Seduction and Betrayal: Host Genes Required for Assault of Salmonella by Bacteriophage P22
… Three of these genes (matA, matB, and matD) mapped to the immediate vicinity of another P22-required maturation gene, opdA, at 80 minutes on the genetic map, but were genetically distinct.
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